Advance Care Planning for Patients with Advanced Cancer

A Prospective, Randomized Trial Assessing the Feasibility of an Advance Care Planning Intervention for Patients Hospitalized in a French Cancer Center

NA · Institut de cancérologie Strasbourg Europe · NCT06149312

This study is testing a new way to help hospitalized patients with advanced cancer understand and plan their care better compared to standard care.

Quick facts

PhaseNA
Study typeInterventional
Enrollment120 (estimated)
Ages18 Years and up
SexAll
SponsorInstitut de cancérologie Strasbourg Europe (other)
Drugs / interventionschemotherapy
Locations1 site (Strasbourg)
Trial IDNCT06149312 on ClinicalTrials.gov

What this trial studies

This study evaluates the feasibility of a systematic Advance Care Planning (ACP) intervention for hospitalized patients with advanced cancer. It is a randomized, single-center trial where one group of patients will receive a structured interview about their care plan, while a control group will receive standard care. The goal is to improve patients' understanding of their care goals, assist with ACP documentation, and potentially influence their illness trajectory during and after hospitalization.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with advanced or metastatic solid cancer who are hospitalized and have not yet completed advance directives.

Not a fit: Patients with hematologic malignancies or those experiencing uncontrolled symptoms that prevent an interview will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could enhance the quality of life and care alignment for patients with advanced cancer.

How similar studies have performed: While specific ACP interventions in this context are understudied, palliative care approaches have shown benefits in similar patient populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 18 years or older
* Patients with a diagnosis of advanced or metastatic solid cancer
* Patients hospitalized in a conventional oncology, radiotherapy or hematology department
* Agreement obtained from the referring oncologist or senior doctor responsible for the patient during hospitalization
* Patient hospitalized for less than 7 days
* Patients who have not yet written advance directives
* Signature of informed consent

Exclusion Criteria:

* Patients treated for hematologic malignancies
* Presence of uncontrolled symptoms that do not allow an interview to be carried out
* Patients with planned hospitalization for chemotherapy or biopsy or performance of a procedure
* Patients \< 18 years old or patients ≥ 18 years old under supervision
* Patients placed under judicial protection or guardianship
* Decompensated neuropsychiatric disorders
* Comprehension problems
* Patients without social security
* Allophone patients

Where this trial is running

Strasbourg

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Neoplasms

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.