Adrenal vein sampling in China

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter observational study enrolling patients with confirmed primary aldosteronism who undergo adrenal venous sampling (AVS). The study will collect detailed clinical, technical, and methodological data on AVS procedures (including access approaches) and treatment decisions made after AVS. Patients will be followed over time for clinical and biochemical outcomes, medication use, and adverse cardiovascular events to link AVS findings with long-term prognosis. The protocol aims to standardize AVS practice and refine procedural methods across participating Chinese centers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with confirmed primary aldosteronism;
2. Patients undergoing adrenal venous sampling for subtype classification of primary aldosteronism.

Exclusion Criteria:

1. Severe comorbidity, including stroke, myocardial infarction, heart failure, severe valvular heart disease, liver cirrhosis, and metastatic tumor within the previous 3 months；
2. An estimated glomerular filtration rate \<45 ml/min/1.73 m2, or serum creatinine \>176 μmol/L；
3. Patients who refuse adrenalectomy;
4. Suspected of having an adrenocortical carcinoma;
5. Allergy to contrast agent;
6. Pregnant, nursing, or planning to become pregnant

Where it's running

• The first affiliated hospital of USTC
  Hefei, Anhui, China Recruiting
• Chuiyangliu Hospital affiliated to Tsinghua University
  Beijing, Beijing Municipality, China Recruiting
• China-Japan Friendship Hospital
  Beijing, Beijing Municipality, China Recruiting
• Peking University First Hospital
  Beijing, Beijing Municipality, China Recruiting
• Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College
  Beijing, Beijing Municipality, China Recruiting
• Peking University People's Hospital
  Beijing, Beijing Municipality, China Recruiting

+26 more sites. See ClinicalTrials.gov for the full list.

Study contacts

• Principal investigator: Hui Dong, MD — Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College
• Study coordinator: Hui Dong, MD
• Email: donghui666@sina.com
• Phone: 86-010-88322385

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.