Adding laser-based antimicrobial therapy to deep cleaning and tongue scraping for bad breath in people with type 2 diabetes and severe gum disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants receive conventional periodontal treatment (scaling and root planing) plus tongue scraping, and some participants also receive antimicrobial photodynamic therapy (aPDT) using methylene blue and a light source. Treatments are given weekly for one month, followed by monthly maintenance visits up to six months. Researchers will compare breath odor measurements and periodontal health outcomes between the groups to see if aPDT provides additional benefit. The trial is conducted at the Bauru School of Dentistry, University of Sao Paulo.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients diagnosed with type 2 diabetes mellitus according to the 2019 WHO criteria
* Stage 3 or 4 periodontitis
* No periodontal treatment in the previous 12 months
* a minimum of 20 remaining teeth.

Exclusion Criteria:

* Smokers
* Alcohol-dependent individuals
* Pregnant or lactating women
* Patients with renal disorders
* Patients using medications that affect the periodontium

Where it's running

• Bauru School of Dentistry
  Bauru, São Paulo, Brazil Recruiting

Study contacts

• Study coordinator: Carla A. Damante, PhD
• Email: cdamante@usp.br
• Phone: +551432266064

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.