Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Adding gestures to speech to help Cantonese speakers with aphasia name words

Official title: Contrasting Effects of Verbal Treatment and Gesture Plus Verbal Treatment for Word Retrieval in Cantonese Speakers With Aphasia

Run by Hong Kong University · NCT07455162 · Data updated 2026-11-12

This study will test whether combining hand gestures with speech therapy helps Cantonese-speaking people with aphasia name words better than speech-only therapy.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment90 (estimated)
SponsorHong Kong University
Academic / other
Locations1 site (Hong Kong)
StatusRecruiting
StartedApril 1, 2025
Main results expectedSeptember 2028
Study endsSeptember 2028
Registry record updatedMarch 11, 2026
Trial IDNCT07455162 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults with chronic aphasia from a unilateral left-hemisphere stroke who are premorbidly fluent in Cantonese, have word-finding difficulty, can repeat single words, and do not have significant cognitive impairment or severe motor-speech/apraxia.

Probably not a fit

People with very mild or very severe aphasia, significant cognitive impairment, major motor speech disorders or non-Cantonese speakers are unlikely to benefit from this specific protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with chronic aphasia after a left-hemisphere stroke who are premorbidly fluent in Cantonese will take part in a repeated-measures design with two treatment phases. In the first phase they will receive verbal-only naming therapy, then after a one-month washout period they will receive gesture-plus-verbal treatment (GVT) in the second phase. The study compares verbal and gesture naming performance at different stimulus levels to see which approach produces greater naming gains. Treatment sessions will be delivered in person at The University of Hong Kong and outcomes measured before and after each phase.

Why it matters

Potential benefit: If successful, adding gestures to speech therapy could improve everyday word-finding and communication for Cantonese-speaking people with aphasia.

How similar studies have gone: Previous research in other languages has shown that gesture-plus-verbal approaches can improve naming in some people with aphasia, but evidence specifically in Cantonese speakers is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed with aphasia
* Demonstrate Word finding Difficulty (WFD)
* Able to repeat single words
* Normal (or corrected) vision and hearing
* Aphasia resulting from a unilateral left hemisphere stroke
* Premorbidly fluent in spoken Cantonese
* Without significant cognitive impairments
* Chronic aphasia resulting from a unilateral left hemisphere stroke

Exclusion Criteria:

* A history of other neurological disorders
* With the above moderate to severe or severe motor speech impairment
* With moderate to severe apraxia of speech
* With very mild or very severe aphasia

Where it's running

  • The University of Hong Kong
    Hong Kong, Hong Kong
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.