Adding dairy to a Canadian Food Guide diet and gut health
Official title: Impact of Dairy Integration Into Canadian Food Guide on Gut Health
Run by Laval University · NCT07257913 · Data updated 2026-11-12
This will test whether adding milk or fermented milk to a Canadian Food Guide–based diet changes gut bacteria, gut permeability, and inflammation in 45–65-year-olds with abdominal obesity and mild metabolic changes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 65 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Laval University Academic / other |
| Locations | 1 site (Québec, Quebec) |
| Status | Recruiting |
| Started | October 6, 2025 |
| Main results expected | August 31, 2026 |
| Study ends | August 31, 2026 |
| Registry record updated | December 2, 2025 |
| Trial ID | NCT07257913 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are 45–65-year-old men and women with waist circumference >80 cm (women) or >94 cm (men) and mildly abnormal lipids or glucose who are non-diabetic and able to attend in-person visits in Québec.
✕Probably not a fit
People with diagnosed diabetes, major cardiovascular or immune disease, recent antibiotic use, lactose intolerance or relevant food allergies, active smoking or pregnancy/lactation are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-blinded crossover trial will enroll about 20 middle-aged men and women with abdominal obesity and slightly deteriorated lipid or glucose profiles. Participants will complete three controlled-feeding phases in random order—each including a short run-in and a period consuming a Canadian Food Guide–based diet with either soy beverage (control), milk, or fermented milk—separated by 14–28 day washouts. The team will collect stool, blood, and permeability measures to profile gut microbiota composition, trans-epithelial permeability, and inflammatory markers. The fully controlled feeding design provides precise nutrient intake to detect short-term effects of dairy versus a plant-based alternative on gut health.
Why it matters
Potential benefit: If successful, the results could show that milk or fermented milk improves gut microbiota balance and reduces gut permeability or inflammation, helping refine dietary guidance for people with abdominal obesity.
How similar studies have gone: Previous controlled-feeding and fermented-dairy studies have shown that diet and fermented milk can modify gut microbiota and some inflammatory markers, but dairy-specific effects in this exact population remain incompletely tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * IMC \< 45 * Waist circumference \> 80 cm (Women) or 94 cm (men) Exclusion Criteria: * History of diabetes (types 1 and 2), CVD, enteropathy, immune diseases or bariatric surgery * Cancer (diagnostic and/or treatment) during the last 5 years * Antibiotic consumption during the last 3 months * Active smoking or cannabis consumption * Lactose intolerance or allergy, any allergies to foods given in the intervention phases * Irregular defecation patterns * Pregnancy/lactation * Inability to speak French
Where it's running
-
Institute of Nutrition and Functional Foods (INAF)
Québec, Quebec, Canada Recruiting
Study contacts
- Principal investigator: Alain Veilleux, PhD — Laval University
- Study coordinator: Alain Veilleux, PhD
- Email: alain.veilleux@fsaa.ulaval.ca
- Phone: 418 656-2131
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.