Adaptive intervention for adolescents after psychiatric care
Adaptive Intervention to Prevent Adolescent Suicidal Behavior Following Psychiatric Hospitalization
This study is testing different support strategies for teenagers at high risk of suicide after leaving psychiatric care to see which combination helps them feel safer and reduces their suicidal thoughts over six months.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 13 Years to 17 Years |
| Sex | All |
| Sponsor | University of Michigan Academic / other |
| Locations | 3 sites (Ann Arbor, Michigan and 2 other locations) |
| Trial ID | NCT05282225 on ClinicalTrials.gov |
What this trial studies
This study examines various technology-augmented strategies to create an effective adaptive intervention for adolescents at high risk of suicide following inpatient psychiatric care. It utilizes a sequential multiple assignment randomized trial (SMART) design, where participants are initially randomized to receive either a motivational interview-enhanced safety plan or that plan with supportive text messages for four weeks post-discharge. Non-responders will be re-randomized to receive additional support through booster calls or portal follow-ups. The goal is to identify the most effective combination of interventions to reduce suicidal behavior and ideation over a six-month follow-up period.
Who should consider this trial
Good fit: Ideal candidates are adolescents who have recently attempted suicide or experienced suicidal ideation within the past week.
Not a fit: Patients with severe cognitive impairments, altered mental status, or those without access to a cell phone may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce the risk of suicide and improve mental health outcomes for adolescents transitioning from inpatient care.
How similar studies have performed: Other studies have shown promise with technology-based interventions for mental health, suggesting potential success for this adaptive approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * A suicide attempt in the last month or (2) past-week suicidal ideation (based on the Columbia-Suicide Severity Rating Scale (C-SSRS). In the absence of C-SSRS ratings in the chart, attending physician indication in the chart of the presence of suicidal ideation within the last week or the presence of a suicide attempt in the last month will be used. Exclusion Criteria: * Adolescent presenting with severe cognitive impairment or with altered mental status (acute psychosis or acute manic state) * Transfer to medical unit or residential placement * No availability of a legal guardian * Adolescent not owning a cell phone.
Where this trial is running
Ann Arbor, Michigan and 2 other locations
- University of Michigan's (Child and Adolescent Psychiatric Inpatient Program) — Ann Arbor, Michigan, United States (Recruiting)
- Henry Ford Health System (Kingwood Hospital) — Detroit, Michigan, United States (Completed)
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States (Recruiting)
Study contacts
- Principal investigator: Ewa Czyz — University of Michigan
- Study coordinator: Ewa Czyz
- Email: ewac@umich.edu
- Phone: 734-764-9466
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.