Adaptive Decision Support for Addiction Treatment: Testing a Care Tool for ED Doctors to Help Buprenorphine Use

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project uses a multiphase optimization strategy to iteratively refine the EMBED CDS interface and workflow in real-time ED settings. Five rapid-cycle rounds compare variations of alerts and CDS components to reduce user errors and disruption while increasing adoption. The aim is to improve how ED physicians follow standard care for initiating buprenorphine in eligible patients. The study progresses through optimization and a follow-up confirmatory phase comparing the optimized system to the original EMBED package. Participating sites are in Connecticut, led by Yale University with NIDA collaboration.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Emergency department patient
* 18 years of age or older
* Moderate to severe opioid use disorder

Exclusion Criteria:

* Under 18 years of age
* Pregnant
* Currently receiving medication for opioid use disorder

Where it's running

• Yale New Haven Shoreline Medical Center
  Guilford, Connecticut, United States Recruiting
• Yale New Haven Hospital- St. Raphael
  New Haven, Connecticut, United States Recruiting
• Yale New Haven Hospital
  New Haven, Connecticut, United States Recruiting

Study contacts

• Principal investigator: Edward Mel, MD, MHS — Yale University
• Study coordinator: Edward Melnick, MD, MHS
• Email: edward.melnick@yale.edu
• Phone: 203-785-4363

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.