Adapted Physical Activity for People with Lower Limb Peripheral Artery Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial aims to determine how muscle strengthening focused on ischemic areas, combined with global muscle strengthening, affects physical capacity in individuals with lower limb peripheral arterial disease and intermittent claudication. Participants have validated lower limb arterial disease, limited walking ability, and no contraindication to exercise, and they undergo an adapted exercise regimen. Outcomes focus on how ischemia-related pain patterns influence walking performance and muscle activity. The study explores whether tailoring the training to ischemic regions improves functional outcomes compared with standard approaches. Relevance is to better understand how biomechanics and ischemia location relate to rehabilitation potential.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with Lower Limb Peripheral Arterial Disease with IPSC \< 0.90, arterial stenosis in the lower limbs and intermittent claudication
* No contraindication to physical activity
* Socially insured patients over 18 ;
* Patient who has signed the consent form.

Exclusion Criteria:

* Severe or unstable cardiopulmonary pathologies, contraindicating exercise training
* Unstable angina or myocardial infarction \<3 months
* Severe rheumatological pathology of the lower limbs
* Amputee of a lower or upper limb fitted with a device
* Extensive dermatosis of the lower limbs
* Known NYHA grade III or IV heart failure
* Known severe respiratory pathology
* Parkinson's disease, hemiplegia or paraplegia
* Adults subject to enhanced protection, deprived of their liberty by judicial or administrative decision
* Persons unable to consent
* Be in a period of exclusion from other interventional research.
* Any event (injury, surgery, etc.) occurring during the protocol period that could have an impact on results.

Where it's running

• Centre Hospitalier Du Mans
  Le Mans, France Recruiting

Study contacts

• Study coordinator: Christelle JADEAU
• Email: cjadeau@ch-lemans.fr
• Phone: 02 44 71 07 81

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.