Adapted acute abdomen guidelines for primary care in Zambia
Official title: Effectiveness of Implementing the Adapted Practice Guidelines for Primary Care of Acute Abdomen in Zambia: An Effectiveness-Implementation Hybrid Type 2 Study Design.
Run by University of Bergen · NCT07587190 · Data updated 2026-11-12
This project tests whether adapting a high-income country guideline for acute abdomen to Zambia and implementing it in primary care can change how long patients stay in the hospital.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 280 (estimated) |
| Sponsor | University of Bergen Academic / other |
| Locations | 1 site (Lusaka, Lusaka Province) |
| Status | Recruiting |
| Started | September 1, 2025 |
| Main results expected | August 31, 2026 |
| Study ends | December 31, 2028 |
| Registry record updated | May 14, 2026 |
| Trial ID | NCT07587190 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years and older with acute abdomen managed at the participating intervention or control sites.
✕Probably not a fit
Patients with trauma-related acute abdomen or those undergoing immediate postoperative care may not benefit from the guideline implementation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study uses a mixed methods design to adapt a guideline for acute abdomen for use in Zambian primary care and to develop strategies to implement it. It collects qualitative and quantitative data from health care workers to tailor the guideline and its rollout. The main outcome is the change in hospital length of stay for patients with acute abdomen at intervention sites compared with control sites. The aim is to see if the adapted guideline can reduce morbidity and mortality by strengthening primary care management. The research addresses gaps in LMIC-specific guidance for acute abdomen management.
Why it matters
Potential benefit: If successful, patients may have shorter hospital stays and improved outcomes due to earlier, guideline-based management at the primary care level.
How similar studies have gone: Previous work shows mixed results for guideline adaptation and implementation in LMICs; this study contributes novel evidence in primary care settings for acute abdomen.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Data from all patients 18 year and older with acute abdomen including surgical, gynecological and medical acute abdomen managed at the intervention site and control site will be collected during the study period. Exclusion Criteria: * All cases of acute abdomen secondary to trauma will be excluded from the study. All patients in the immediate postoperative phase operated from other facilities presenting with acute abdomen.
Where it's running
-
Kanyama First Level Hospital and Matero First Level Hospital
Lusaka, Lusaka Province, Zambia Recruiting
Study contacts
- Study coordinator: Wilson Mbewe, MD
- Email: wimbe8573@uib.no
- Phone: +260977466316
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.