Assessing plaque burden and ischemia in patients with MINOCA

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate coronary artery plaque burden, perivascular inflammation, and the extent of myocardial ischemia in patients who experience acute myocardial infarction but have non-obstructive coronary artery disease (MINOCA). Participants will undergo CT coronary angiography to identify coronary artery anatomy and plaque characteristics, as well as stress [12N] NH3 PET-MR to assess myocardial ischemia. The study seeks to provide insights into the underlying mechanisms of MINOCA, which may lead to improved diagnostic and therapeutic strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Acute chest pain
* Elevated troponin
* Non-obstructive coronary arteries by coronary angiography

Exclusion Criteria:

* Obstructive coronary artery disease
* Contraindications against CT coronary angiography or stress \[12N\] NH3 PET-MR
* Not able to give informed consent

Where it's running

• Department of Clinical Science, University of Bergen
  Bergen, Norway Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.