Acute Creatine Gummies vs. Powder in Healthy Adults
Official title: Acute Pharmacokinetics of Create Wellness Gummies in Healthy Adults
Run by University of Oklahoma · NCT07579455 · Data updated 2026-11-12
This study tests whether Create Wellness creatine gummies raise blood creatine levels differently than creatine monohydrate powder in healthy adults after a single dose.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | All |
| Enrollment | 16 (estimated) |
| Sponsor | University of Oklahoma Academic / other |
| Locations | 1 site (Norman, Oklahoma) |
| Status | Recruiting |
| Started | June 2026 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | May 28, 2026 |
| Trial ID | NCT07579455 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18-45 with BMI <35 kg/m2 who are recreationally active and healthy.
✕Probably not a fit
Individuals with kidney, liver, lung disease, cancer, or who take medications affecting the outcomes, or those currently using creatine monohydrate, may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Healthy adults aged 18-45 will fast and avoid certain activities before two visits in which blood creatine levels are measured at multiple time points after taking either the gummies or the powder. The trial uses a cross-checking design to compare acute changes in blood creatine following ingestion of the two forms. Participants undergo screening, informed consent, height/weight, body composition, and hydration assessments, then provide blood samples at baseline and at several intervals up to five hours post-dose. Results will indicate if the gummy form produces similar, higher, or lower immediate creatine bioavailability compared with the traditional powder.
Why it matters
Potential benefit: If gummies provide similar absorption, they could offer a convenient alternative to creatine powder.
How similar studies have gone: Prior work in this area has shown comparable acute creatine absorption between different formulations in healthy individuals, but direct gummy-vs-powder comparisons are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults between the ages of 18-45 yrs * Body mass index of \<35 kg/m2 * Recreationally active \[(≥30 minutes of moderate-intensity physical activity per week as defined by the International Physical Activity Questionnaire (IPAQ)\] * Healthy and free from major diseases as determined from screening call and health history questionnaire. * Agrees to complete pre-assessment guidelines (8-hour fast from caloric foods and beverages, 24-hour abstention from vigorous physical activity, caffeine, alcohol, and tobacco). Exclusion Criteria: * Chronic kidney disease, liver disease, chronic obstructive pulmonary disease, or cancer. * Currently using medications that may directly impact the primary outcomes including: diuretics and corticosteroids). * Currently using creatine monohydrate * Severely impaired hearing or speech or inability to speak English.
Where it's running
-
ATHENA Laboratory
Norman, Oklahoma, United States Recruiting
Study contacts
- Principal investigator: Sam R Moore, PhD — University of Oklahoma
- Study coordinator: Sam R. Moore, PhD
- Email: samray@ou.edu
- Phone: 4053252542
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.