Acupoint TENS vs. Resistance Training for Iron Deficiency Anemia in Women
Official title: Effect of Transcutaneous Electrical Acupoint Stimulation Versus Resistance Exercise on Hemoglobin Level in Women With Iron Deficiency Anemia
Run by Cairo University · NCT07605676 · Data updated 2026-11-12
This trial tests whether acupoint transcutaneous electrical nerve stimulation (Acu-TENS) or resistance exercise, in addition to standard care, can raise hemoglobin levels in women with iron deficiency anemia.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 20 Years to 30 Years |
| Sex | Women only |
| Enrollment | 60 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | January 15, 2026 |
| Main results expected | August 15, 2026 |
| Study ends | October 15, 2026 |
| Registry record updated | May 26, 2026 |
| Trial ID | NCT07605676 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women aged 20–30 with WHO-defined moderate IDA (8.0–10.9 g/dL) due to heavy menstrual bleeding, not currently pregnant, and stable on the concurrent medical treatment plan.
✕Probably not a fit
Patients with non-IDA causes of anemia, severe anemia (Hb < 8.0 g/dL), pregnancy, chronic kidney or liver disease, or active malignancy may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Sixty women aged 20–30 with moderate iron deficiency anemia will be randomized into three groups to compare Acu-TENS, resistance exercise, or routine medical care only over 12 weeks. The study measures changes in hemoglobin and several blood and functional parameters, using a pretest–posttest RCT design. Interventions are delivered three times per week, alongside standard treatment. The trial aims to determine which approach, if any, provides greater improvements in anemia-related outcomes.
Why it matters
Potential benefit: If successful, the approach could offer nonpharmacologic options to help raise hemoglobin and improve quality of life for women with IDA.
How similar studies have gone: Prior studies suggest nonpharmacologic approaches can influence hematologic and functional outcomes, but this exact comparison is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Sixty women diagnosed with iron deficiency anemia within ≤6 months. * Their hemoglobin concentrations ranging from 8.0 to 10.9 g/dL that classified as moderate anemia in accordance with the World Health Organization (WHO) criteria. * The iron deficiency anemia resulted from the heavy monthly bleeding of menstrual cycle as reported by the women. * Their age will be ranged from 20 and 30 years old. * Their BMI will be ranged from 18.5 to 24.9 kg/m². * They will have the same level of functional capacity assessed by 6-minute walking test. * They will be receiving the same medical treatment programme. Exclusion Criteria: * Other causes of anemia (e.g., hemolytic anemia, anemia of chronic disease, megaloblastic anemia, thalassemia, or sickle cell disease). * Severe anemia (hemoglobin \< 8.0 g/dL) * History of chronic kidney disease, liver disease, or malignancy. * Current pregnancy or lactation, due to altered iron metabolism and hemoglobin thresholds. * Recent blood transfusion or iron therapy (oral or intravenous) within the past 3 months. * Use of hematopoietic agents (e.g., erythropoietin). * Acute infection or inflammatory conditions at the time of enrollment. * Inability or unwillingness to provide informed consent or comply with study procedures. * Previous participation in complementary treatments/research within the last six months.
Where it's running
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Kafrelsheikh University
Cairo, Egypt Recruiting
Study contacts
- Principal investigator: Nagwa Mohamed Hamed Badr, PhD — Cairo University
- Study coordinator: Dina Ebrahim Mohamed Aboshady, BSc PT
- Email: dinaaboshady2020@gmail.com
- Phone: 0201010481505
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.