Ablation Index-guided treatment for ventricular tachycardia in heart disease patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of Ablation Index (AI)-guided catheter ablation for treating ventricular tachycardia in patients with ischemic cardiomyopathy. The study compares outcomes of AI-guided ablation to traditional methods without AI guidance. By utilizing advanced technology to monitor lesion quality and depth during the procedure, the trial aims to improve patient outcomes and reduce the recurrence of arrhythmias. The research is particularly focused on patients with structural heart disease and prior myocardial infarction.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient ≥ 18 y.o.
* Structural Heart Disease: Ischemic Cardiomyopathy
* Sustained Scar-related Monomorphic Ventricular Tachycardia documented by ECG or CIED interrogation

Exclusion Criteria:

* If clinical ventricular arrhythmia is predominantly PVCs, supraventricular tachycardia, or ventricular fibrillation
* Myocardial infarction or cardiac surgery within 6 months
* Severe mitral regurgitation
* Stroke or TIA within 6 months
* Prior VT substrate ablation in the previous 6 months
* NYHA functional class IV
* Non-ischemic VT substrate

Where it's running

• Rush University Medical Center
  Chicago, Illinois, United States Recruiting
• Mass General Brigham and Women's Hospital
  Boston, Massachusetts, United States Not yet recruiting
• Medical University of Michigan
  Ann Arbor, Michigan, United States Not yet recruiting
• Mayo Clinic
  Rochester, Minnesota, United States Not yet recruiting
• Medical University of South Carolina
  Charleston, South Carolina, United States Not yet recruiting

Study contacts

• Principal investigator: Alexander Mazur, MD — Rush University Medical Center
• Study coordinator: Alexander Mazur, MD
• Email: alexander_mazur@rush.edu
• Phone: 312-942-5020

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Sphere VT: Using Sphere-9 Catheter and Affera System to treat recurrent scar-related ventricular tachycardia

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.