A smartphone symptom-management app for children early after cancer treatment and their caregivers

Development and Evaluation of a Symptom Management Mobile Health Application With Personalised Support for Children at the Early Stage of Cancer Survivorship and Their Caregivers

NA · Chinese University of Hong Kong · NCT05748210

This project will test whether a mobile app plus personalized nurse support can help Chinese-speaking children aged 9–16 who recently finished cancer treatment and their primary caregivers have fewer symptoms and better quality of life after three months.

Quick facts

PhaseNA
Study typeInterventional
Enrollment150 (estimated)
Ages9 Years to 16 Years
SexAll
SponsorChinese University of Hong Kong (other)
Locations2 sites (Hong Kong and 1 other locations)
Trial IDNCT05748210 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial will assign paediatric cancer survivors and their primary caregivers to either immediate access to a symptom-management mobile app with 12 weeks of personalized nurse support or to a wait-list control. Eligible children are aged 9–16, have completed active cancer treatment within the past two years, can read Chinese, and have a smartphone or tablet; their primary caregivers must also be Chinese-speaking and willing to use the app. Key outcomes measured at baseline and three months include children's physical function, anxiety, depressive symptoms, fatigue, peer relationships, and pain interference, and caregiver quality of life. The intervention combines app-based symptom tracking, tailored self-management content, and interactive nurse support, while the control group receives the app after the waiting period.

Who should consider this trial

Good fit: Ideal candidates are Chinese-speaking children aged 9–16 who finished active cancer treatment within the past two years, own a smartphone or tablet, and have a primary caregiver willing to use the app.

Not a fit: Children with cognitive impairment, active psychiatric illness, evidence of recurrence or secondary malignancy, or families without Chinese-language smartphone access are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, the app could reduce symptom burden and improve quality of life for young cancer survivors and their caregivers by providing accessible, ongoing symptom monitoring and nurse-guided support.

How similar studies have performed: While mobile health interventions have shown promise for symptom management in adult and some pediatric oncology settings, evidence specific to early pediatric cancer survivorship is limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Chinese paediatric cancer survivors will be included if they

* are aged 9 to 16 years,
* are able to read Chinese and communicate in Chinese,
* have completed active cancer treatment (within the previous 2 years), as early symptom management support is crucial to reduce the symptom burden in survivors and their caregivers throughout their survivorship, and
* have a smartphone or tablet and are willing to install the mHealth app.

The primary caregiver of the paediatric cancer survivors (either the mother or father)

* are able to read Chinese and communicate in Chinese, and
* have a smartphone or tablet and are willing to install the mHealth app with their children surviving cancer.

Exclusion Criteria:

Chinese paediatric cancer survivors will be excluded if they

* have cognitive impairments or psychiatric illnesses
* are currently participating in other symptom management studies, or
* have evidence of secondary malignancy or recurrence

The primary caregivers of the paediatric cancer survivors (either the mother or father) will be excluded if they have cognitive impairments or psychiatric illnesses.

Where this trial is running

Hong Kong and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Oncology, Survivorship, symptom management, cancer, children, caregiver, mobile health

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.