Clinical trial Recruiting at 3 sites Interventional Ages 18 and up

A resilience-based approach to improve long-term quality of life for lymphoma survivors

Official title: Thriving Beyond Treatment: A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship.

Run by Massachusetts General Hospital · NCT07013435 · Data updated 2026-11-12

This trial tests whether a resilience-focused program helps lymphoma survivors feel a better quality of life compared with a health-education program.

More Lymphoma trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment254 (estimated)
SponsorMassachusetts General Hospital
Academic / other
Drugs / interventionschemotherapy, immunotherapy, radiation
Locations3 sites (Miami, Florida and 2 other locations)
StatusRecruiting
StartedOctober 6, 2026
Main results expectedSeptember 2029
Study endsAugust 2030
Registry record updatedOctober 26, 2026
Trial IDNCT07013435 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) who are English or Spanish speaking, within 1–5 years of completing active lymphoma treatment (including maintenance), and able to participate in virtual sessions.

Probably not a fit

Individuals with active psychiatric, medical, or cognitive conditions, or inability to participate in virtual group sessions, may not benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers are testing a resilience and mind-body program called SMART3RP-Lymphoma to see if it improves long-term quality of life for people who have completed lymphoma treatment. The program uses techniques such as imagery, relaxation, yoga, cognitive strategies, and positive psychology, delivered in eight weekly online group sessions. Participants will complete four surveys over 12 months and provide hair cortisol samples to assess stress. The study compares SMART3RP-Lymphoma to a Health Education Program to determine its impact on quality of life and resiliency in survivors.

Why it matters

Potential benefit: If successful, participants may experience better quality of life and coping after cancer treatment.

How similar studies have gone: Past studies using resilience and mind-body approaches have shown improvements in quality of life for cancer survivors, but this specific lymphoma-focused program is a targeted, newer adaptation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English or Spanish speaking adults (18+ at time of enrollment)
* Within 1-5 years of completing active treatment for lymphoma (includes surgery, chemotherapy, immunotherapy, radiation therapy, or other); individuals may be on maintenance treatment.

Exclusion Criteria:

* Active psychiatric, medical concern or cognitive comorbidity as determined by the site PI or treating clinician

Where it's running

  • Sylvester Comprehensive Cancer Center
    Miami, Florida, United States
    Recruiting
  • Mass General Hospital
    Boston, Massachusetts, United States
    Recruiting
  • Huntsman Cancer Institute
    Salt Lake City, Utah, United States
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.