A program to help overweight adults lose weight and reduce weight bias through self-compassion

A Self-compassion Focused Intervention for Internalized Weight Bias and Weight Loss

Not applicable Interventional East Carolina University · NCT05987306

This study is testing a new weight loss program that helps overweight adults lose weight and feel better about themselves by combining standard weight loss methods with self-compassion exercises.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorEast Carolina University Academic / other
Locations2 sites (Greenville, North Carolina and 1 other locations)
Trial IDNCT05987306 on ClinicalTrials.gov

What this trial studies

This clinical trial tests a new approach to weight loss that combines standard weight loss strategies with self-compassion exercises for overweight adults who experience internalized weight bias. Over a 12-week period, participants will engage in weekly sessions conducted via videoconferencing, focusing on both weight loss and reducing negative self-perceptions related to weight. The program is modeled after the Diabetes Prevention Program and incorporates Kristen Neff's self-compassion intervention. The goal is to determine if this combined approach can lead to significant weight loss and a decrease in internalized weight bias.

Who should consider this trial

Good fit: Ideal candidates are overweight adults aged 18 and older with a BMI of 25 or higher and moderate to high levels of internalized weight bias.

Not a fit: Patients with uncontrolled medical conditions, recent cardiovascular events, or those currently on weight loss medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could provide a holistic approach to weight loss that not only helps individuals lose weight but also improves their self-esteem and mental health.

How similar studies have performed: While the combination of self-compassion and weight loss interventions is relatively novel, similar studies have shown promise in addressing weight bias and improving mental health outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* BMI ≥ 25, ≥ 18 years old
* Smartphone access
* WBIS score ≥ 4

Exclusion Criteria:

* Type I diabetes, uncontrolled hypertension, cardiovascular event in past year, any major active kidney, liver, cardio, or cerebrovascular disease,
* musculoskeletal problems that would prevent physical activity,
* current weight loss medication or weight loss program,
* history of bariatric surgery,
* pregnant or breastfeeding,
* eating disorder except binge eating disorder

Where this trial is running

Greenville, North Carolina and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Overweight and Obesity
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.