A program to help frail elderly patients prepare for hip and knee replacement surgery
Getting Fit for Hip and Knee Replacement: The FitJoints Multisite Randomized Controlled Trial of a Multi-modal Intervention in Frail Patients With Osteoarthritis
This study is testing a new program to help frail older adults get ready for hip or knee replacement surgery to see if it can improve their recovery after the operation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 192 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | McMaster University Academic / other |
| Locations | 4 sites (Calgary, Alberta and 3 other locations) |
| Trial ID | NCT05100966 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of a multimodal frailty reduction intervention for patients awaiting elective hip or knee replacement surgery. It aims to improve post-surgical outcomes by addressing the needs of frail elderly individuals, particularly in light of increased wait times due to the COVID-19 pandemic. The intervention can be delivered either in person or virtually, following international guidelines on frailty reduction. This is the first multi-site randomized controlled trial to explore this approach, which is crucial given the rising number of frail patients in need of surgery.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 60 and older who are pre-frail or frail and are scheduled for elective unilateral total hip or knee replacement surgery.
Not a fit: Patients with renal disorders, neuromuscular disorders, active cancer, inflammatory arthritis, or those unable to communicate in English without a caregiver will not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly enhance recovery and functional outcomes for frail elderly patients undergoing joint replacement surgery.
How similar studies have performed: Other studies have shown promise in using multimodal interventions for frailty reduction, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pre-frail (score of 1 or 2) or frail (score of 3-5) * ≥ 60 years old * Receiving elective unilateral total hip or knee replacement * Waiting time for surgery is estimated to be between 4 to 15 months Exclusion Criteria: * Renal disorder * A neuromuscular disorder * Active cancer * Inflammatory arthritis * Unable to speak or understand English and has no caregiver for translation * Participating in another trial that involves protein supplementation * Participating in an exercise program
Where this trial is running
Calgary, Alberta and 3 other locations
- Foothill Medical Centre - Alberta Health Services — Calgary, Alberta, Canada (Not_yet_recruiting)
- Juravinski Hospital - Hamilton Health Sciences — Hamilton, Ontario, Canada (Recruiting)
- St. Joseph's Healthcare — Hamilton, Ontario, Canada (Not_yet_recruiting)
- University Hospital - London Health Sciences Centre — London, Ontario, Canada (Not_yet_recruiting)
Study contacts
- Principal investigator: Alexandra Papaioannou — McMaster University
- Study coordinator: Alexandra Papaioannou, MD, MSc
- Email: papaioannou@hhsc.ca
- Phone: (905) 521-2100
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.