A program to help frail elderly patients prepare for hip and knee replacement surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of a multimodal frailty reduction intervention for patients awaiting elective hip or knee replacement surgery. It aims to improve post-surgical outcomes by addressing the needs of frail elderly individuals, particularly in light of increased wait times due to the COVID-19 pandemic. The intervention can be delivered either in person or virtually, following international guidelines on frailty reduction. This is the first multi-site randomized controlled trial to explore this approach, which is crucial given the rising number of frail patients in need of surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pre-frail (score of 1 or 2) or frail (score of 3-5)
* ≥ 60 years old
* Receiving elective unilateral total hip or knee replacement
* Waiting time for surgery is estimated to be between 4 to 15 months

Exclusion Criteria:

* Renal disorder
* A neuromuscular disorder
* Active cancer
* Inflammatory arthritis
* Unable to speak or understand English and has no caregiver for translation
* Participating in another trial that involves protein supplementation
* Participating in an exercise program

Where it's running

• Juravinski Hospital - Hamilton Health Sciences
  Hamilton, Ontario, Canada Recruiting
• Foothill Medical Centre - Alberta Health Services
  Calgary, Alberta, Canada Not yet recruiting
• St. Joseph's Healthcare
  Hamilton, Ontario, Canada Not yet recruiting
• University Hospital - London Health Sciences Centre
  London, Ontario, Canada Not yet recruiting

Study contacts

• Principal investigator: Alexandra Papaioannou — McMaster University
• Study coordinator: Alexandra Papaioannou, MD, MSc
• Email: papaioannou@hhsc.ca
• Phone: (905) 521-2100

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.