Clinical trial Recruiting at 4 sites Interventional Ages 65 and up

A program combining music and activities to promote healthy aging

Official title: A Multi-domain Intervention to Constrast Cognitive Decline in Healthy Aging

Run by University of Bari · NCT06767410 · Data updated 2026-11-12

This study is testing whether a program that combines music, exercise, and social activities can help older adults keep their minds sharp and improve their overall brain health.

Quick facts

Study typeInterventional
Ages65 Years and up
SexAll
Enrollment100 (estimated)
SponsorUniversity of Bari
Academic / other
Locations4 sites (Adelfia, Bari and 3 other locations)
StatusRecruiting
StartedOctober 1, 2025
Main results expectedJune 1, 2027
Study endsDecember 2027
Registry record updatedJanuary 9, 2025
Trial IDNCT06767410 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are elderly individuals aged 65 and older who live independently and are not musically trained.

Probably not a fit

Patients with severe cognitive or functional impairments or those with musical expertise may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the long-term effects of a multidomain intervention designed for community-dwelling elderly individuals to prevent cognitive decline. Participants will engage in various activities, including music training, physical exercise, and social interactions, over a 9-month period. The study aims to assess changes in Brain-Derived Neurotrophic Factor (BDNF) levels and cognitive functions through pre- and post-intervention evaluations. Participants will be divided into groups to compare the effects of music-inclusive activities against non-musical and passive control groups.

Why it matters

Potential benefit: If successful, this intervention could enhance cognitive health and quality of life for elderly individuals by promoting neuroplasticity and reducing frailty.

How similar studies have gone: While similar interventions have shown promise in enhancing cognitive functions and social engagement, this specific approach combining music and multiple activities is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 65
* Living independently

Exclusion Criteria:

* Musical expertise
* Severe cognitive or functional impairment

Where it's running

  • Musica In Gioco
    Adelfia, Bari, Italy
    Recruiting
  • University of Bari
    Bari, Bari, Italy
    Recruiting
  • Centro Servizi per la famiglia Libertà
    Bari, Bari, Italy
    Recruiting
  • ANAS Puglia (Associazione Nazionale di Azione Sociale)
    Bari, Bari, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.