A practical program using emotional awareness and expression therapy for Veterans with chronic musculoskeletal pain

A Pragmatic Trial of Emotional Awareness and Expression Therapy for Veterans With Chronic Pain: Phase 1

Not applicable Interventional University of California, Los Angeles · NCT07218757

This project will try emotional awareness and expression therapy (EAET) versus cognitive behavioral therapy to see if it helps Veterans with moderate-to-severe musculoskeletal chronic pain feel less pain and have fewer mental-health symptoms.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment84 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of California, Los Angeles Academic / other
Locations1 site (Los Angeles, California)
Trial IDNCT07218757 on ClinicalTrials.gov

What this trial studies

This is a phase 1 pragmatic pilot that will implement Emotional Awareness and Expression Therapy (EAET) delivered by clinicians in usual-care settings across up to seven VA healthcare systems. Veterans with at least three months of musculoskeletal pain and average pain ≥4/10 will be enrolled and receive EAET or cognitive behavioral therapy for chronic pain (CBT-CP). The project focuses on real-world delivery, clinician training, feasibility, and effects on pain severity, pain interference, depression, anxiety, and PTSD symptoms. Results will inform a larger effectiveness trial and broader VA implementation.

Who should consider this trial

Good fit: Veterans aged 18 or older receiving care at a participating VA site who have had at least three months of musculoskeletal pain and report average pain of 4/10 or higher are the intended participants.

Not a fit: Patients with poorly controlled major psychiatric illness, active suicide or violence risk, or severe uncontrolled substance use disorder are unlikely to benefit or be eligible for participation.

Why it matters

Potential benefit: If successful, the therapy approach could reduce pain severity, improve function, and lessen mental-health symptoms for Veterans with chronic musculoskeletal pain.

How similar studies have performed: Multiple controlled and uncontrolled trials in civilians and Veterans, including two single-site VA trials that showed EAET outperformed CBT-CP in older Veterans, have reported promising results for EAET.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Veteran at one of 7 VA healthcare systems;
* Age 18 years or older;
* At least 3 months of musculoskeletal pain, defined using International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) diagnostic codes, which include the following M-code diagnoses: back pain, fibromyalgia, limb pain, neck pain; R-code diagnoses: pelvic and perineal pain, jaw pain; and G-code diagnoses: tension headaches; and
* Pain of at least moderate severity, defined as ≥4 "on average" on the 0-10 Numeric Pain Rating Scale

Exclusion Criteria:

* Poorly controlled major psychiatric illness (e.g., schizophrenia, bipolar I disorder with acute psychotic symptoms, severe manic or depressive episode listed as active in CPRS);
* Active suicide or violence risk (e.g., currently suicidal or homicidal ideation, intent, or plans);
* Active severe drug/alcohol use disorder (e.g., drinking more than intended, tried to stop but couldn't, spent significant time drinking or being sick from aftereffects, wanted drink so badly you couldn't think of anything else, interference with home or work life, continued to drink despite problems, given up on activities, dangerous situations, withdrawal and/or tolerance); and
* Current participation in CBT-CP or EAET, or participation in either intervention in the last 6 months, via clinical care or another research study.

Where this trial is running

Los Angeles, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Musculoskeletal PainChronic PainPsychotherapyMusculoskeletal DiseaseMental Health
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.