A digital platform for understanding genetic risks of heart diseases
Official title: MyGeneRank: A Digital Platform for Next-Generation Genetic Studies
Run by Scripps Translational Science Institute · NCT03277365 · Data updated 2026-11-12
This study tests whether giving people information about their genetic risk for heart disease can help them make better health choices and improve their lifestyles.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100000 (estimated) |
| Sponsor | Scripps Translational Science Institute Academic / other |
| Locations | 1 site (La Jolla, California) |
| Status | Recruiting |
| Started | September 26, 2017 |
| Main results expected | February 11, 2026 |
| Study ends | September 2030 |
| Registry record updated | April 17, 2024 |
| Trial ID | NCT03277365 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are customers of 23andMe who are willing to share their genetic data and use an Apple mobile device.
✕Probably not a fit
Patients under 18 years old will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to explore how genetic risk factors influence health decisions and lifestyle choices related to heart diseases, particularly coronary artery disease (CAD). Participants will receive a genetic risk score based on their 23andMe data, which ranks their genetic risk compared to global populations. By understanding their genetic predisposition, individuals may be better equipped to make informed health decisions. The study focuses on the interplay between genetic risk and controllable health behaviors.
Why it matters
Potential benefit: If successful, this could empower patients to make informed lifestyle choices to mitigate their genetic risk for heart diseases.
How similar studies have gone: Other studies have shown success in using genetic risk scores to inform health decisions, making this approach promising but not entirely novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Customer of 23andMe willing to share their 23andMe data * User of Apple mobile device Exclusion Criteria: * Under 18 years old
Where it's running
-
Scripps Translational Science Institute
La Jolla, California, United States Recruiting
Study contacts
- Study coordinator: Jennifer Wagner, RN
- Email: generank@scripps.edu
- Phone: 858-784-2028
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.