A biorepository for cancer research and precision medicine
Official title: The Caris Biorepository Research Protocol
Run by Caris Science, Inc. · NCT01499394 · Data updated 2026-11-12
This study is collecting and storing samples from cancer patients to help researchers find better treatments and improve care for people with cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100000 (estimated) |
| Sponsor | Caris Science, Inc. Industry-sponsored |
| Locations | 38 sites (Mobile, Alabama and 37 other locations) |
| Status | Recruiting |
| Started | November 2010 |
| Main results expected | November 2030 |
| Study ends | November 2035 |
| Registry record updated | January 21, 2026 |
| Trial ID | NCT01499394 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who can provide informed consent.
✕Probably not a fit
Patients who are prisoners or minors, as well as those unable to give informed consent, will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Caris Biorepository collects and stores biological specimens and clinical data to support research aimed at advancing precision medicine in cancer care. This observational project aims to provide researchers and healthcare professionals with access to high-quality human specimens and associated data, facilitating the correlation of clinical outcomes with biospecimen information. By maintaining the integrity and relevance of these specimens, the biorepository seeks to enhance drug development, clinical trials, and healthcare policies. The initiative fosters collaboration among various entities, including government, academia, and industry, to improve patient outcomes.
Why it matters
Potential benefit: If successful, this biorepository could significantly enhance the understanding of cancer treatments and improve personalized care for patients.
How similar studies have gone: Other biorepositories have shown success in advancing cancer research and precision medicine, indicating that this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older * Capacity to provide informed consent Exclusion Criteria: * Due to the complexity of state and federal requirements governing the participation of prisoners in research, prisoners-patients will not be approached for participation in the Caris Biorepository. * Minor subjects will not be included in the Caris Biorepository, as it is possible biospecimens and data may be stored beyond the time limitations of assent and it may be impracticable to re-consent these subjects once they become adults. * Individuals who lack the capacity to give informed consent
Where it's running
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University of South Alabama
Mobile, Alabama, United States Recruiting -
Southwest Medical Imaging
Scottsdale, Arizona, United States Recruiting -
St. Bernards Medical Center
Jonesboro, Arkansas, United States Recruiting -
CARTI Cancer Center
Little Rock, Arkansas, United States Recruiting -
ObjectiveHealth - ARcare Center for Clinical Research
Little Rock, Arkansas, United States Recruiting -
Lee Memorial Health System
Fort Myers, Florida, United States Recruiting
Show 32 more locations
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Cancer Care of North Florida
Lake City, Florida, United States Recruiting -
Advent Health
Orlando, Florida, United States Recruiting -
The University of South Florida
Tampa, Florida, United States Recruiting -
Cleveland Clinic Florida
Weston, Florida, United States Recruiting -
Phoebe Putney Memorial Hospital
Albany, Georgia, United States Recruiting -
Emory University
Atlanta, Georgia, United States Recruiting -
Augusta University Research Institute
Augusta, Georgia, United States Recruiting -
Cancer Center of Middle Georgia
Dublin, Georgia, United States Recruiting -
Hope and Healing Cancer Services
Hinsdale, Illinois, United States Recruiting -
CHRISTUS - St. Frances Cabrini Hospital
Alexandria, Louisiana, United States Recruiting -
Tulane University
New Orleans, Louisiana, United States Recruiting -
CHRISTUS - Highland Medical Center
Shreveport, Louisiana, United States Recruiting -
Mercy Medical Center
Baltimore, Maryland, United States Recruiting -
Sinai Hospital of Baltimore
Baltimore, Maryland, United States Recruiting -
Hattiesburg Clinic
Hattiesburg, Mississippi, United States Recruiting -
Jackson Oncology Associates
Jackson, Mississippi, United States Recruiting -
University of Mississippi Medical Center
Jackson, Mississippi, United States Recruiting -
ObjectiveHealth - Premier Health Research
Sparta, New Jersey, United States Recruiting -
CHRISTUS - St. Vincent Regional Cancer Center
Santa Fe, New Mexico, United States Recruiting -
St. Lawrence Health System
Potsdam, New York, United States Recruiting -
National Translational Research Group
Ridge, New York, United States Recruiting -
Altru Health System
Grand Forks, North Dakota, United States Recruiting -
NEO Urology Associates
Boardman, Ohio, United States Recruiting -
Great Lakes Medical Research
Cleveland, Ohio, United States Recruiting -
Bend Memorial Clinic
Bend, Oregon, United States Recruiting -
Clinical Biotechnology Research Institute at RSFH
Charleston, South Carolina, United States Recruiting -
Spartanburg Regional Health Services
Spartanburg, South Carolina, United States Recruiting -
West Cancer Center
Germantown, Tennessee, United States Recruiting -
ObjectiveHealth - Amarillo Premier Research
Amarillo, Texas, United States Recruiting -
CHRISTUS - St. Michael's Health
Texarkana, Texas, United States Recruiting -
CAMC Clinical Trials
Charleston, West Virginia, United States Recruiting -
Mercy Health
Janesville, Wisconsin, United States Recruiting
Study contacts
- Principal investigator: Matthew Oberley, MD — Caris Life Sciences
- Study coordinator: Mary Baker
- Email: carisresearch@carisls.com
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.