3D evaluation of swelling after wisdom tooth removal
Three-dimensional Evaluation of Postoperative Edema After Third Molar Surgery: a Randomized Clinical Trial
PHASE4 · Implantology Institute · NCT05941130
This study is testing whether a mix of steroids and anti-inflammatory drugs can help reduce swelling and pain after wisdom tooth removal for patients who need this surgery.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Sex | All |
| Sponsor | Implantology Institute (other) |
| Locations | 1 site (Lisbon) |
| Trial ID | NCT05941130 on ClinicalTrials.gov |
What this trial studies
This study investigates the postoperative edema and pain experienced by patients undergoing third molar surgery using three-dimensional imaging technology. It aims to assess the effectiveness of a combination of corticosteroids and non-steroidal anti-inflammatory drugs in reducing inflammation and improving recovery outcomes. By analyzing facial swelling through advanced imaging techniques, the study seeks to standardize postoperative care and enhance patients' quality of life following surgery. The research will involve patients classified as ASA grade I or II who require surgical extraction of impacted third molars.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals requiring surgical extraction of fully or partially impacted third molars and classified as ASA grade I or II.
Not a fit: Patients with active bleeding, coagulation disorders, or those who are pregnant or lactating may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of postoperative symptoms and enhanced recovery experiences for patients undergoing third molar surgery.
How similar studies have performed: Previous studies have shown varying success with corticosteroid use in similar surgical contexts, but the application of 3D imaging for edema assessment is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals requiring surgical extraction of fully or partially impacted third molars requiring osteotomy; * Individuals classified as grade I or II of the American Society of Anesthesiologists (ASA) * Individuals with compliance to cooperate with the research protoco Exclusion Criteria: * Individuals with active bleeding or coagulation disorders * Individuals with history of intolerance or hypersensitivity to the drugs included in the postoperative medication protocol * Pregnant or lactating women * Individuals with cysts or tumors around the embedded third molar * Individuals who did not attend the control visits.
Where this trial is running
Lisbon
- Implantology Institute — Lisbon, Portugal (RECRUITING)
Study contacts
- Principal investigator: Catarina Pinto, DDS — Implantology Institute
- Study coordinator: Duarte Marques, DDS PhD
- Email: d.marques@institutoimplantologia.com
- Phone: +351 217 210 980
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Molar, Third, Third Molar Surgery, Soft Tissue Swelling, Pain, Postoperative, Quality of Life, Third molar surgery, Three-dimensional imaging, postoperative Pain