3 Tesla MRI measurements of facial skin muscles in people with facial paralysis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with chronic facial paralysis and healthy volunteers will undergo high-resolution 3 Tesla MRI to obtain morphometric measurements (thickness, volume) of superficial facial muscles, with special attention to the zygomaticus major. Images will be analyzed to quantify muscle atrophy and compare affected sides to the contralateral side and to controls. The goal is to produce objective muscle metrics that could inform surgical planning (for example, choosing between hypoglossal-facial anastomosis, temporalis elongation myoplasty, or free muscle transfer) and track recovery after reconstructive procedures. Adults with MRI contraindications, pregnancy, or lactation are excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subject, for which a diagnosis of facial paralysis has been made, female or male, over 18 years of age.

Exclusion Criteria:

* Pregnancy and lactation,
* a patient with a contra-indication to MRI (Claustrophobia, Pace Maker, Neurosurgical Clips, Vascular Clips, Cardiac Valves, V.peritoneal Valves, Cochlear Implant, Neuro-Stimulator, Intra-Orbital Metal Shards (Articular Prosthesis, Dental Prosthesis, Contact Glass, Insulin Pumps, Intrauterine Device, Tattoo, Piercing / Implants.))

Where it's running

• CHU Amiens Picardie
  Amiens, Picardie, France Recruiting

Study contacts

• Study coordinator: Stéphanie DAKPE, Dr
• Email: dakpe.stephanie@chu-amiens.fr
• Phone: +33322668322

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.