Exploring the link between facial paralysis and homocysteine levels
Official title: The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients
Run by Afyonkarahisar Health Sciences University · NCT06742580 · Data updated 2026-11-12
This study looks at whether higher levels of a substance in the blood called homocysteine are linked to Bell's palsy in adults who suddenly experience facial weakness or paralysis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Afyonkarahisar Health Sciences University Academic / other |
| Locations | 3 sites (Afyonkarahisar and 2 other locations) |
| Status | Recruiting |
| Started | December 1, 2023 |
| Main results expected | April 1, 2025 |
| Study ends | August 4, 2025 |
| Registry record updated | December 19, 2024 |
| Trial ID | NCT06742580 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults who have been admitted with acute facial paralysis.
✕Probably not a fit
Patients with facial paralysis due to trauma, tumors, or central nervous system diseases are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the relationship between idiopathic acute peripheral facial paralysis, commonly known as Bell's palsy, and blood homocysteine levels in adult patients. Bell's palsy is characterized by sudden facial muscle weakness or paralysis, often accompanied by pain and sensory changes. The study aims to determine if elevated homocysteine levels, which are associated with thrombotic disorders, play a role in the etiology of this condition. Patients with acute facial paralysis will be observed, while those with specific exclusions such as trauma or central nervous system diseases will not be included.
Why it matters
Potential benefit: If successful, this study could provide insights into the role of homocysteine in Bell's palsy, potentially leading to new treatment strategies.
How similar studies have gone: While the relationship between homocysteine and thrombotic disorders has been studied, the specific link to Bell's palsy remains novel and untested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Patients admitted with acute facial paralysis Exclusion Criteria: * Facial and ear trauma or tumor * İatrogenic * Cholesteatoma * Facial paralysis due to central nervous system diseases
Where it's running
-
Afyonkarahisar Health Sciences University
Afyonkarahisar, Turkey (Türkiye) Recruiting -
Afyonkarahisar Health Sciences University
Afyonkarahisar, Turkey (Türkiye) Recruiting -
Afyonkarahisar Health Sciences University
Afyonkarahisar, Turkey (Türkiye) Active not recruiting
Study contacts
- Principal investigator: Orhan Kemal KAHVECİ, PROFESSOR — Afyon Health Sciences University Hospital
- Study coordinator: Murat Akin, Assistant Doctor
- Email: makin.md279@gmail.com
- Phone: +90 272 246 33 35
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Intradermal acupuncture for ocular surface problems after intractable facial paralysis
This study will test whether tiny needles placed just under the skin can improve dry eye and other ocular surface symptoms in adults with persistent peripheral facial paralysis.
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Intradermal acupuncture and self-rehabilitation for severe Bell's Palsy
This study is testing if a combination of acupuncture and a self-rehabilitation program can help people with severe Bell's Palsy recover better than other treatments.
-
Laser acupuncture treatment for Bell's palsy
This study is testing if laser acupuncture can help people with Bell's palsy feel better compared to standard treatments and a fake treatment.
-
Comparing Prednisolone and Cerebrolysin for treating Bell's Palsy
This study is testing whether Prednisolone or Cerebrolysin works better to help people with Bell's Palsy recover and avoid complications.
-
Evaluating Korean medicine for treating Bell's palsy
This study is testing if Korean medicine can help adults with Bell's palsy improve their facial function and overall condition over three months.
-
Combined neural mobilization with proprioceptive therapy for Bell’s palsy facial symmetry
A randomized trial tests whether adding neural mobilization to proprioceptive neuromuscular facilitation helps improve facial symmetry in people with Bell’s palsy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.