Clinical trial Recruiting at 2 sites Observational Ages 18 to 80

Exploring the link between facial paralysis and homocysteine levels

Official title: The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients

Run by Afyonkarahisar Health Sciences University · NCT06742580 · Data updated 2026-11-12

This study looks at whether higher levels of a substance in the blood called homocysteine are linked to Bell's palsy in adults who suddenly experience facial weakness or paralysis.

More Bell Palsy trials

Quick facts

Study typeObservational
Ages18 Years to 80 Years
SexAll
Enrollment80 (estimated)
SponsorAfyonkarahisar Health Sciences University
Academic / other
Locations3 sites (Afyonkarahisar and 2 other locations)
StatusRecruiting
StartedDecember 1, 2023
Main results expectedApril 1, 2025
Study endsAugust 4, 2025
Registry record updatedDecember 19, 2024
Trial IDNCT06742580 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults who have been admitted with acute facial paralysis.

Probably not a fit

Patients with facial paralysis due to trauma, tumors, or central nervous system diseases are unlikely to benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between idiopathic acute peripheral facial paralysis, commonly known as Bell's palsy, and blood homocysteine levels in adult patients. Bell's palsy is characterized by sudden facial muscle weakness or paralysis, often accompanied by pain and sensory changes. The study aims to determine if elevated homocysteine levels, which are associated with thrombotic disorders, play a role in the etiology of this condition. Patients with acute facial paralysis will be observed, while those with specific exclusions such as trauma or central nervous system diseases will not be included.

Why it matters

Potential benefit: If successful, this study could provide insights into the role of homocysteine in Bell's palsy, potentially leading to new treatment strategies.

How similar studies have gone: While the relationship between homocysteine and thrombotic disorders has been studied, the specific link to Bell's palsy remains novel and untested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Patients admitted with acute facial paralysis

Exclusion Criteria:

* Facial and ear trauma or tumor
* İatrogenic
* Cholesteatoma
* Facial paralysis due to central nervous system diseases

Where it's running

  • Afyonkarahisar Health Sciences University
    Afyonkarahisar, Turkey (Türkiye)
    Recruiting
  • Afyonkarahisar Health Sciences University
    Afyonkarahisar, Turkey (Türkiye)
    Recruiting
  • Afyonkarahisar Health Sciences University
    Afyonkarahisar, Turkey (Türkiye)
    Active not recruiting

Study contacts

  • Principal investigator: Orhan Kemal KAHVECİ, PROFESSOR — Afyon Health Sciences University Hospital
  • Study coordinator: Murat Akin, Assistant Doctor
  • Email: makin.md279@gmail.com
  • Phone: +90 272 246 33 35

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.