Exploring the link between facial paralysis and homocysteine levels
The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients
This study looks at whether higher levels of a substance in the blood called homocysteine are linked to Bell's palsy in adults who suddenly experience facial weakness or paralysis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Afyonkarahisar Health Sciences University Academic / other |
| Locations | 3 sites (Afyonkarahisar and 2 other locations) |
| Trial ID | NCT06742580 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between idiopathic acute peripheral facial paralysis, commonly known as Bell's palsy, and blood homocysteine levels in adult patients. Bell's palsy is characterized by sudden facial muscle weakness or paralysis, often accompanied by pain and sensory changes. The study aims to determine if elevated homocysteine levels, which are associated with thrombotic disorders, play a role in the etiology of this condition. Patients with acute facial paralysis will be observed, while those with specific exclusions such as trauma or central nervous system diseases will not be included.
Who should consider this trial
Good fit: Ideal candidates for this study are adults who have been admitted with acute facial paralysis.
Not a fit: Patients with facial paralysis due to trauma, tumors, or central nervous system diseases are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the role of homocysteine in Bell's palsy, potentially leading to new treatment strategies.
How similar studies have performed: While the relationship between homocysteine and thrombotic disorders has been studied, the specific link to Bell's palsy remains novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Patients admitted with acute facial paralysis Exclusion Criteria: * Facial and ear trauma or tumor * İatrogenic * Cholesteatoma * Facial paralysis due to central nervous system diseases
Where this trial is running
Afyonkarahisar and 2 other locations
- Afyonkarahisar Health Sciences University — Afyonkarahisar, Turkey (Türkiye) (Active_not_recruiting)
- Afyonkarahisar Health Sciences University — Afyonkarahisar, Turkey (Türkiye) (Recruiting)
- Afyonkarahisar Health Sciences University — Afyonkarahisar, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Orhan Kemal KAHVECİ, PROFESSOR — Afyon Health Sciences University Hospital
- Study coordinator: Murat Akin, Assistant Doctor
- Email: makin.md279@gmail.com
- Phone: +90 272 246 33 35
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.