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Clinical trials and research at Vanda Pharmaceuticals

• 13Clinical trials
• 7Countries

Newest trials

All recruiting trials (13)

• Ponesimod for moderately to severely active ulcerative colitis: a treatment study

  This study tests whether ponesimod can help people with moderately to severely active ulcerative colitis who have not responded well to other treatments.

  Recruiting at 2 sites Phase 3 Vanda Pharmaceuticals · Chula Vista, California and 1 other locations · NCT07686081

• Tradipitant for GLP-1R agonist–related nausea and vomiting in adults with overweight or class I–II obesity

  This trial will test if tradipitant can reduce nausea and vomiting caused by GLP-1 receptor agonist weight-loss medicines in adults who are overweight or have class I–II obesity.

  Recruiting at 3 sites Phase 3 Vanda Pharmaceuticals · Los Angeles, California and 9 other locations · NCT07446439

• Ponesimod in adults with moderate-to-severe chronic plaque psoriasis

  This study tests whether ponesimod is safe and helps clear moderate-to-severe plaque psoriasis in adults aged 18–65.

  Recruiting at 10 sites Phase 3 Vanda Pharmaceuticals · Glendale, Arizona and 9 other locations · NCT07362017

• Eight-week test of VSJ-110 versus placebo for dry eye

  This eight-week test will see if VSJ-110 reduces dry eye symptoms better than a placebo in adults with dry eye.

  Recruiting at 2 sites Phase 2 Vanda Pharmaceuticals · Newport Beach, California and 4 other locations · NCT07179055

• Iloperidone for adults with uncontrolled high blood pressure

  We are testing whether iloperidone can lower blood pressure in adults whose blood pressure stays high despite at least 8 weeks of one or more blood pressure medications.

  Recruiting at 18 sites Phase 2 Vanda Pharmaceuticals · Phoenix, Arizona and 27 other locations · NCT07090161

• Testing whether stopping iloperidone long-acting injection causes symptom return in adults with schizophrenia.

  This trial tests whether iloperidone long-acting injection prevents symptom worsening compared with placebo in adults with schizophrenia.

  Recruiting at 22 sites Phase 3 Vanda Pharmaceuticals · Rogers, Arkansas and 21 other locations · NCT06961968

• Evaluating Tasimelteon for Pediatric Insomnia

  This study is testing if a new sleep medication called tasimelteon can help children and teenagers aged 2 to 17 with insomnia sleep better compared to a placebo.

  Recruiting at 34 sites Phase 3 Vanda Pharmaceuticals · Dothan, Alabama and 34 other locations · NCT06953869

• Evaluating milsaperidone for treating major depressive disorder

  This study is testing if adding milsaperidone to the treatment plan can help people with major depressive disorder who haven't felt better with their current antidepressants.

  Recruiting at 50 sites Phase 3 Vanda Pharmaceuticals · Phoenix, Arizona and 52 other locations · NCT06830044

• Evaluating Tasimelteon for Delayed Sleep-Wake Phase Disorder

  This study is testing if a new sleep medication called tasimelteon can help people with Delayed Sleep-Wake Phase Disorder who have a specific genetic variant improve their sleep patterns.

  Recruiting Phase 3 Vanda Pharmaceuticals · Çankaya, Ankara · NCT06701396

• Evaluating the safety of iloperidone in adolescents with schizophrenia or bipolar disorder

  This study is testing how safe the medication iloperidone is for teenagers aged 12 to 17 who have schizophrenia or bipolar disorder.

  Recruiting at 11 sites Phase 4 Vanda Pharmaceuticals · Dothan, Alabama and 10 other locations · NCT05648591

• Tolerability of trichostatin A for people with relapsed or refractory blood cancers

  This trial will test whether trichostatin A is safe and tolerable for adults whose blood cancers have come back or stopped responding to treatment.

  Recruiting at 4 sites Phase 1 Vanda Pharmaceuticals · Washington D.C., District of Columbia and 10 other locations · NCT03838926

• Creating a database to understand sleep issues in Smith-Magenis Syndrome

  This study is collecting information about sleep problems in people with Smith-Magenis Syndrome to help understand and manage these issues better.

  Recruiting Vanda Pharmaceuticals · Washington D.C., District of Columbia · NCT03154697

• Registry for blind individuals with sleep problems

  This study is creating a registry for totally blind people with sleep problems to gather information that can help researchers understand and address their sleep issues better.

  Recruiting Vanda Pharmaceuticals · Washington D.C., District of Columbia · NCT01195558

Quick answers

How many clinical trials run by Vanda Pharmaceuticals are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (12 trials), Poland (3 trials), Bulgaria (1 trial), Czechia (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 7, Phase 2: 2, Phase 4: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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