Sponsor or institution
Clinical trials and research at Southern Illinois Univ at Edwardsville
As of November 12, 2026, Find a Trial lists 8 NIH-funded research projects at this institution, with $1.8 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 8NIH research projects
NIH-funded research (8)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Targeting LAT1 in cancer with new non-amino acid inhibitors
A cancer-focused project aims to block LAT1 transporters using new non-amino acid compounds to slow cancer growth with fewer side effects.
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Targeting the protein-translation hub eIF4F to fight cancer
A new drug-like approach aims to block a key protein interaction that helps cancer cells grow and resist treatment, with participation possible by patients in future studies.
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Dopamine-and-sigma receptor drug for Alzheimer's
Researchers are trying a new small-molecule drug that acts on dopamine and sigma brain receptors to help memory, thinking, and behavior in people with Alzheimer's disease.
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Blocking the tumor protein-making machine (eIF4F) to slow cancer
This project is creating small drug-like molecules to block a key protein interaction that lets many cancers make excess proteins, with the hope of helping patients whose tumors resist standard treatments.
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Investigating a new treatment for Alzheimer's disease using mixed receptor modulators
This study is looking at a new treatment for Alzheimer's disease using a small molecule called AM73, which might help improve brain function and behavior in mice, with hopes that it could lead to better options for people living with Alzheimer's.
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Targeting a key protein interaction to improve cancer treatment
This study is looking for new medicines that can block a specific interaction between two proteins that help cancer cells grow and resist treatment, with the hope of finding better ways to fight cancer.
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Investigating how temperature affects enzyme reactions and their efficiency
This study looks at how temperature affects the way proteins work in enzymes, which could help scientists create better drugs for patients by understanding how these enzymes speed up chemical reactions in the body.
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How proteins that change DNA structure affect brain cell communication and memory.
This study is looking at how a protein called Kismet helps brain cells communicate by influencing the structure of connections between them, which is important for understanding conditions that affect brain development, and it also gives students a chance to get involved in research.
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