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Clinical trials and research at Prisma Health-Upstate

• 6Clinical trials
• 2NIH research projects
• 1Country

Newest trials

All recruiting trials (6)

• Boosting medication start and stay rates for people with opioid use disorder by adding peer support at mobile clinics

  This project will test whether adding trained peer support specialists at Prisma Health mobile clinics helps adults with opioid use disorder start and stay on medication treatment.

  Recruiting Prisma Health-Upstate · Greenville, South Carolina · NCT07541417

• E-cigarette flavor options as harm reduction for people on buprenorphine

  This project will test whether switching to different flavored e-cigarettes helps adults with opioid use disorder who are taking buprenorphine reduce harms from smoking cigarettes.

  Recruiting Prisma Health-Upstate · Greenville, South Carolina · NCT07202039

• Intracervical vasopressin to help hysteroscopic removal of retained pregnancy tissue.

  This test checks whether injecting vasopressin into the cervix during hysteroscopic removal helps women 18–51 have complete removal of retained pregnancy tissue.

  Recruiting Phase 4 Prisma Health-Upstate · Greenville, South Carolina · NCT07102615

• Pre-surgery acetazolamide to reduce shoulder pain after laparoscopic hysterectomy

  This study will test whether a single preoperative dose of acetazolamide reduces shoulder and abdominal pain in women undergoing total laparoscopic hysterectomy.

  Recruiting Phase 4 Prisma Health-Upstate · Greenville, South Carolina · NCT07101250

• Two sperm preparation methods to lower sperm DNA damage and improve embryo development

  This will test whether using the LensHooke CA0 device on partner sperm lowers DNA fragmentation and affects fertilization, embryo development, and pregnancy outcomes for couples undergoing ICSI.

  Recruiting Prisma Health-Upstate · Greenville, South Carolina · NCT06990841

• Assessing cancer risk in individuals

  This study is testing how personal history, lifestyle, and biological samples can help identify people at higher risk of developing cancer so they can get the right care.

  Recruiting Prisma Health-Upstate · Greenville, South Carolina · NCT04947098

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• NCORP of the Carolinas: Community-based cancer care research network

  A community-based cancer research program in the Carolinas aims to bring cutting-edge cancer care research and quality-of-life studies into everyday clinical settings.

  NIH research Prisma Health - Upstate · Greenville, United States · NIH-11543457

• Improving medical education on sex and gender health

  This study is working to improve how medical teachers and students learn about the important roles that sex and gender play in health, so they can better understand and care for patients like you.

  NIH research Prisma Health - Upstate · Greenville, United States · NIH-10915585

Quick answers

How many clinical trials run by Prisma Health-Upstate are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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