Sponsor or institution
Clinical trials and research at OHSU Knight Cancer Institute
As of November 12, 2026, Find a Trial lists 37 clinical trials run by OHSU Knight Cancer Institute that are recruiting, in United States. By phase: Phase 2 (11), Phase 1 (6), Phase 4 (3), Phase 1/2 (3). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 37Clinical trials
- 1Country
Newest trials
All recruiting trials (37)
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Intraoperative Methadone for Postoperative Pain in Head and Neck Cancer Patients
This trial tests whether giving methadone during surgery, in addition to standard fentanyl, helps control pain after head and neck cancer surgery more effectively than fentanyl alone.
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Low-Dose Sirolimus for RUNX1-Related Platelet Disorder
This study tests whether a low daily dose of sirolimus is safe and feasible for adults with RUNX1 familial platelet disorder who may be at risk for cancer progression.
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ctDNA-based monitoring in muscle-invasive bladder cancer
This study tests whether a blood-based ctDNA test can flag residual or returning disease in adults with muscle-invasive bladder cancer undergoing standard treatments.
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A tailored web program to boost exercise and healthy eating for pancreatic cancer patients before surgery
This trial tests a personalized web portal called COMPASS to help adults with stage I–III pancreatic cancer who are receiving neoadjuvant chemotherapy to improve exercise and dietary habits.
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Ruxolitinib with azacitidine maintenance after reduced-intensity stem cell transplant for AML
This study tests different doses of ruxolitinib first alone, then with azacitidine maintenance, in adults with acute myeloid leukemia undergoing reduced-intensity allogeneic stem cell transplantation to see if it is safe and tolerable and may help prevent relapse.
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GET FIT Together: a socially enhanced exercise program for older men with prostate cancer
This program tests whether adding structured social support to supervised online exercise reduces cancer-related loneliness and improves mental and physical health in men 65 and older who have had prostate cancer.
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Gruticibart to Prevent Catheter-Related Blood Clots
This phase II trial tests whether a single dose of gruticibart can prevent blood clots caused by a central venous catheter in adults.
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Mipping density before a mammogram with Ulipristal Acetate
This phase 2 study tests whether taking ulipristal acetate before a screening mammogram helps reduce breast density in people with dense breasts to improve imaging.
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Morning versus afternoon immunotherapy for advanced or metastatic solid tumors
This trial tests whether giving standard immune checkpoint inhibitor therapy in the morning versus the afternoon changes outcomes for adults with advanced or metastatic solid tumors.
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Exercise Together for patients with primary brain tumors and their caregivers
A supervised, partner-based exercise program is being tested to see if it’s safe and helps patients with primary brain tumors and their caregivers feel better and function more easily.
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Induction and consolidation using fludarabine, cytarabine, idarubicin, and venetoclax for acute myeloid leukemia
This trial tests whether adding venetoclax to induction and consolidation chemotherapy (fludarabine, cytarabine, and idarubicin) helps adults 18–65 with newly diagnosed acute myeloid leukemia or high-blast myelodysplastic syndrome achieve deeper remissions than standard cytarabine/daunorubicin therapy.
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OMO-103 for advanced or metastatic pancreatic ductal adenocarcinoma
This trial tests an experimental IV drug called OMO-103 to see if it changes tumor cells in adults with locally advanced or metastatic pancreatic ductal adenocarcinoma.
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Spinal injections of cytarabine, methotrexate, and hydrocortisone to prevent severe CAR T neurotoxicity
This phase II test tries whether giving intrathecal cytarabine, methotrexate, and hydrocortisone around day 4 (with a day 7 hydrocortisone if no symptoms) can prevent severe neurotoxicity in adults receiving Yescarta or Tecartus CAR T-cell therapy.
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Evaluating vaccine responses in patients with multiple myeloma and non-Hodgkin lymphoma after CAR-T treatment
This study tests how well vaccines work in people with multiple myeloma and non-Hodgkin lymphoma after they have received CAR-T treatment.
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Observing sex differences in symptoms during cancer immunotherapy
This study looks at the different symptoms men and women experience during cancer immunotherapy to see how their reports match up with what doctors observe.
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Treatment for newly diagnosed monocytic acute myeloid leukemia using a combination of venetoclax and chemotherapy
This study is testing a new treatment combining venetoclax and chemotherapy to see if it helps people with newly diagnosed monocytic acute myeloid leukemia feel better and live longer.
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Glofitamab plus ibrutinib and obinutuzumab for mantle cell lymphoma
This trial will see if combining glofitamab with ibrutinib and obinutuzumab is safe and effective for adults with previously untreated, high‑risk or age‑65‑and‑older mantle cell lymphoma.
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Combining iadademstat with azacitidine and venetoclax for newly diagnosed acute myeloid leukemia
This study is testing a new combination of medications for people with newly diagnosed acute myeloid leukemia who can't have intensive chemotherapy to see if it helps them feel better and live longer.
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Using creative arts to help children with cancer
This study is testing if doing creative arts like drawing and painting can help children with cancer feel better and improve their quality of life compared to just watching videos.
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Combining axatilimab, retifanlimab, and paclitaxel for advanced solid tumors
This study is testing a new combination of three medications to see if they can help people with advanced solid tumors feel better and improve their treatment outcomes.
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Treatment of untreated high grade B cell lymphoma with mosunetuzumab and chemotherapy
This study is testing if a new treatment combining mosunetuzumab and chemotherapy can help people with untreated high grade B cell lymphoma feel better and achieve a complete response.
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Using indocyanine green to predict leaks after pancreas surgery
This study is testing if a special dye given during pancreas surgery can help doctors predict if patients will have leaks after the operation.
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Using amiodarone to prevent atrial fibrillation after esophageal cancer surgery
This study is testing if the heart medication amiodarone can help prevent atrial fibrillation in patients recovering from esophageal cancer surgery.
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Partnered exercise program for couples during cancer treatment
This study tests whether a partnered exercise program can help couples stay healthy during radiation treatment for breast and prostate cancer compared to just receiving exercise information.
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Online weight loss and exercise program for prostate cancer survivors
This study is testing an online weight loss and exercise program to see if it helps men with prostate cancer who have had hormone therapy feel healthier and improve their quality of life.
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Combination treatment for untreated chronic lymphocytic leukemia and small lymphocytic lymphoma
This study is testing a new combination of three medications to see if it can help people with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma feel better and live longer.
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Evaluating PSMA Changes in Prostate Cancer After Hormonal Therapy
This study is testing how hormonal therapy changes a specific protein in men with prostate cancer to see if those changes can help doctors understand the cancer better.
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Using olanzapine to help cancer patients regain appetite and manage weight loss
This study is testing if the medication olanzapine can help cancer patients who are losing weight and have a poor appetite feel better and gain weight while they are receiving treatment.
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Effects of fiber supplements on gut bacteria in the colon
This study is testing if taking daily fiber supplements can change the gut bacteria in the colon to help prevent precancerous polyps.
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Using blood tests to improve treatment strategies for rectal cancer
This study is testing if measuring tumor DNA in the blood can help doctors see how well treatments are working for people with stage II-III rectal cancer.
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Using pemigatinib after chemotherapy for newly diagnosed acute myeloid leukemia
This study is testing if adding a new drug called pemigatinib after standard chemotherapy can help people with newly diagnosed acute myeloid leukemia recover better and stay safe.
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Lutetium-177 DOTATATE for Stage IV or Recurrent Breast Cancer
This study tests whether 177Lu-DOTATATE can shrink or slow the growth of breast cancer that has spread or come back in patients whose tumors express SSTR2.
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Identifying and caring for individuals with inherited cancer syndromes
This study is testing whether free genetic testing can help find and support people with inherited cancer syndromes better than current methods.
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Targeted therapy for pancreatic cancer using new drugs
This study is testing new targeted therapies for pancreatic cancer to see how well they work and if they are safe for patients at different stages of the disease.
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Ruxolitinib plus venetoclax, with or without azacitidine, for relapsed or refractory AML
This phase 1 trial tests whether adding ruxolitinib to venetoclax, with or without azacitidine, is safe and helps adults whose AML has returned or not responded to prior treatment.
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Using FMISO PET/MRI to assess brain tumors
This study is testing a new imaging method using a special dye and scans to see if it can help doctors understand the oxygen levels in brain tumors and how they grow.
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Using gadolinium and ferumoxytol MRI to diagnose central nervous system abnormalities
This study is testing if using two different MRI contrast agents, gadolinium and ferumoxytol, can help better diagnose problems in the central nervous system for patients with suspected abnormalities.
Quick answers
How many clinical trials run by OHSU Knight Cancer Institute are recruiting right now?
37, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 11, Phase 1: 6, Phase 4: 3, Phase 1/2: 3. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.