Sponsor or institution

Clinical trials and research at Lankenau Institute for Medical Research

• 9NIH research projects

NIH-funded research (9)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Keeping heart muscle cells connected as the heart ages

  This project looks at whether strengthening the physical links between heart muscle cells can help aging hearts keep working better.

  NIH research Lankenau Institute for Medical Research · Wynnewood, United States · NIH-11520493

• Mechanotransduction in Disease: Creating Mouse Models to Study Mechanical Signals

  A new mouse model project aims to understand how cells sense and respond to mechanical forces and how disruptions can contribute to diseases like heart disease, asthma, and cancer.

  NIH research Lankenau Institute for Medical Research · Wynnewood, United States · NIH-11520491

• New ways to trigger tissue regrowth in young and aged animals

  This grant studies how to make damaged tissues regrow by triggering the body's own regenerative pathways, using a mouse model to understand how to restore jaw bone and surrounding tissues.

  NIH research Lankenau Institute for Medical Research · Wynnewood, United States · NIH-11330404

• How the IDO2 protein shapes harmful and protective immune responses in autoimmune disease

  This project looks at the protein IDO2 to understand how it makes immune cells cause or prevent autoimmune disease, aiming to help people with conditions like inflammatory arthritis.

  NIH research Lankenau Institute for Medical Research · Wynnewood, United States · NIH-11257303

• Understanding how to regrow lost or damaged body tissues

  This research explores how to encourage the body to naturally regrow its own tissues, like bone and cartilage, by activating a special pathway.

  NIH research Lankenau Institute for Medical Research · Wynnewood, United States · NIH-11099990

• Understanding how cancer begins when a key cell process is disrupted

  This research aims to understand how liver cancer starts when a specific cell control system, called the Rb/E2f interaction, stops working correctly.

  NIH research Lankenau Institute for Medical Research · Wynnewood, United States · NIH-11095720

• Understanding how IDO2 affects immune responses in autoimmune diseases

  This study is looking at how a specific enzyme called IDO2 in immune cells might be causing problems in autoimmune diseases like arthritis, and it aims to find new ways to help people with these conditions feel better without the harsh side effects of current treatments.

  NIH research Lankenau Institute for Medical Research · Wynnewood, United States · NIH-11044418

• Understanding how disruptions in cell cycle regulation can lead to cancer

  This study is looking at how certain proteins in our cells work together and how their loss might lead to liver cancer, hoping to find new ways to treat it and help patients understand what causes this disease.

  NIH research Lankenau Institute for Medical Research · Wynnewood, United States · NIH-10854953

• Investigating a key pathway involved in diabetes complications

  This study is looking at how a substance called 3-deoxyglucosone (3DG) affects people with diabetes, especially in causing kidney problems, and it's using mice to find out more about it so that new treatments can be developed to help manage diabetes better.

  NIH research Lankenau Institute for Medical Research · Wynnewood, United States · NIH-10766705

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