WGS-based pathogen profiling to combat antimicrobial resistance in veterinary settings
Official title: ADRDL Diagnostic testing support for the FDA CVM VET-LIRN program
Funded at South Dakota State University · NIH-11403009 · Data updated 2026-11-12
This grant supports using whole genome sequencing at a veterinary lab to help track and reduce antimicrobial resistance in bacteria from animals.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | South Dakota State University NIH-funded |
| Lab location | 1 site (Brookings, United States) |
| Project start | September 10, 2018 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $75,000 |
| NIH project number | 5U18FD006558-09 |
| Project ID | NIH-11403009 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are animal patients from which bacterial isolates are obtained and then sequenced for resistance profiling.
✕Less likely to help
Healthy animals or samples without resistant organisms may not directly benefit.
What this research studies
A South Dakota lab will act as a core facility to perform whole genome sequencing on bacterial isolates received from five partner labs. They will confirm species with MALDI-TOF, extract DNA, and sequence genomes to create public data that Vet-LIRN can use to understand resistance patterns. The work aims to inform evidence-based actions to reduce antimicrobial resistance in veterinary contexts. Results will be shared in public repositories to support broader use by researchers and practitioners.
Why it matters
Potential benefit: If successful, the project could improve how veterinarians prevent and respond to resistant infections in animals.
How similar studies have gone: Previous sequencing-based surveillance efforts have shown how genomic data can illuminate resistance trends and inform interventions.
Where this research is happening
-
South Dakota State University
Brookings, United States Active
Researchers
- Principal investigator: Ruesch, Laura — South Dakota State University
- Study coordinator: Ruesch, Laura
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.