Interactive, reproducible enrichment-analysis tool for cancer-related genes
Official title: An interactive and reproducible tool for enrichment analysis
Funded at South Dakota State University · NIH-11391398 · Data updated 2026-11-12
A user-friendly, web-based tool helps researchers understand how gene changes relate to cancer biology in a clear, interactive way.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | South Dakota State University NIH-funded |
| Lab location | 1 site (Brookings, United States) |
| Project start | September 16, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $251,062 |
| NIH project number | 5R01HG013534-03 |
| Project ID | NIH-11391398 on NIH RePORTER |
Who could benefit from this research
✓Could help
Researchers and clinicians working with cancer genomics and wanting to interpret gene lists and pathways.
✕Less likely to help
Direct patient participation is not part of this grant; benefits are indirect through enhanced research insights.
What this research studies
This project builds on a prototype of ShinyGO to make enrichment analysis easier, faster, and more reproducible for scientists who may not be computational experts. It focuses on cancer-promoting genes and related pathways by linking gene lists to GO, KEGG, Reactome, and other resources, with visualizations and gene feature details. The goal is to empower bench researchers to interpret large transcriptomic and proteomic datasets without heavy programming, improving clarity and rigor in analyses. The tool aims to be robust, up-to-date, and well-documented to support ongoing cancer research efforts.
Why it matters
Potential benefit: If successful, patients and researchers could benefit from faster, more reliable insights into cancer biology that may inform future therapies and experiments.
How similar studies have gone: ShinyGO has been widely used and cited, indicating demand and usefulness, but the project notes gaps in development, debugging, and documentation that this grant seeks to address.
Where this research is happening
-
South Dakota State University
Brookings, United States Active
Researchers
- Principal investigator: Ge, Xijin — South Dakota State University
- Study coordinator: Ge, Xijin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.