Weight gain prevention before quitting: helping 30+ adults with obesity quit smoking
Official title: A multiple health behavior change intervention for people with obesity who smoke cigarettes: a randomized clinical trial
Funded at Brown University · NIH-11225230 · Data updated 2026-11-12
A weight gain prevention program is offered to adults with obesity who smoke, to help them lose weight and build confidence before starting smoking cessation.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brown University NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | July 1, 2026 |
| Project end | April 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $733,445 |
| NIH project number | 1R01DA061886-01A1 |
| Project ID | NIH-11225230 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (18+) with obesity (BMI ≥ 30) who currently smoke and are motivated to quit.
✕Less likely to help
Individuals without obesity, or those not planning to quit smoking soon, may not benefit from this pre-quit prevention approach.
What this research studies
This trial pairs an 8-week remote weight gain prevention program with pre-quit planning for adults with obesity who smoke. Participants are randomly assigned to either the weight-focused program or a standard lifestyle education program, then proceed to smoking-cessation treatment. The goal is to see if preventing weight gain improves mood, self-efficacy, and readiness to quit. The study uses self-regulation strategies to support weight loss before attempting to quit smoking.
Why it matters
Potential benefit: If successful, participants may quit smoking more easily and maintain weight loss, improving overall health.
How similar studies have gone: Previous work has shown weight management can support smoking cessation, but applying it specifically before quit attempts in obesity-focused populations is less studied.
Where this research is happening
-
Brown University
Providence, United States Active
Researchers
- Principal investigator: Murphy, Cara — Brown University
- Study coordinator: Murphy, Cara
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.