Virtual support for managing statin-related muscle symptoms

Development, testing, and implementation of virtual statin associated muscle symptom (SAMS) management

NIH-funded research Utah State Higher Education System--University of Utah · NIH-11192251

A virtual program to help adults with atherosclerotic cardiovascular disease manage muscle symptoms from statins so more people can stay on heart-protecting medicine.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUtah State Higher Education System--University of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-11192251 on NIH RePORTER

What this research studies

This project will create, test, and put into practice a remote program to help people who get muscle aches or weakness they believe are caused by statins. Care will combine nurse or pharmacist-led follow-up, provider-facing health IT, patient self-management tools, and psychology-informed support to address fears and misconceptions about statins. The team will use dose adjustments, switching statins, or alternate-day dosing when appropriate and guide safe re-challenge so patients can try staying on therapy. The goal is to make a practical virtual approach clinics can adopt to improve long-term statin use.

Who could benefit from this research

Good fit: Adults (21+) with atherosclerotic cardiovascular disease or who are prescribed statins who have experienced or are worried about statin-related muscle symptoms are ideal candidates.

Not a fit: People without statin-associated muscle symptoms, those with confirmed severe statin-induced muscle injury, or those unable to use telehealth technology are unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, more patients could safely continue statin therapy and reduce their risk of heart attacks and strokes.

How similar studies have performed: Changing dose or type of statin and team-based follow-up have helped many patients continue therapy, but delivering that care fully virtually for SAMS is relatively new.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.