NIH-funded research R21 grant

Vector-capacity of the invasive Anopheles stephensi mosquito in Ethiopia

Official title: Vectorial Capacity of Invasive Anopheles stephensi in Ethiopia

Funded at University of California-Irvine · NIH-11455143 · Data updated 2026-11-12

This grant studies how the invasive Anopheles stephensi mosquito spreads malaria in urban Ethiopia and how it might affect transmission to people.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine
NIH-funded
Lab location1 site (Irvine, United States)
Project startAugust 13, 2026
Project endJuly 1, 2028
Funding year2026
Award (this year)$196,250
NIH project number1R21AI190786-01A1
Project IDNIH-11455143 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are communities in urban Ethiopian areas where An. stephensi is present and malaria transmission is a concern, plus researchers studying vector biology.

Less likely to help

Communities without An. stephensi or malaria risk from this vector may see limited direct benefit.

What this research studies

Researchers at UC Irvine will look at how An. stephensi survives, bites people, and passes malaria parasites under real-world field conditions in Ethiopia. They will test vector competence for local strains of Plasmodium falciparum and P. vivax and estimate overall malaria transmission risk in urban settings. Findings could refine malaria risk maps and help guide targeted control strategies in African cities where this mosquito is spreading.

Why it matters

Potential benefit: If successful, results could improve malaria risk predictions and inform more effective vector control in urban areas affected by An. stephensi.

How similar studies have gone: Previous work has shown that An. stephensi can transmit malaria parasites in various settings, but field-based vectorial capacity assessments in Africa are still developing.

Where this research is happening

  • University of California-Irvine
    Irvine, United States
    Active

Researchers

  • Principal investigator: Yan, Guiyun — University of California-Irvine
  • Study coordinator: Yan, Guiyun

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.