Using ultrasound to enhance treatment for chronic wounds
A theranostic ultrasound approach to improve chronic wound treatment using phase-change contrast agents
This study is exploring a new way to help heal stubborn wounds by using ultrasound and special agents that can boost the delivery of antibiotics right where they're needed, making it easier for patients with chronic wounds to fight off infections and heal better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10913590 on NIH RePORTER |
What this research studies
This research investigates a novel approach to improve the treatment of chronic wounds by utilizing ultrasound technology combined with phase-change contrast agents. These agents can enhance the delivery of antibiotics directly to infected areas, particularly targeting biofilms that hinder healing. The study aims to address the significant challenge of bacterial infections in chronic wounds, which often lead to severe complications such as amputations. By improving antibiotic efficacy, the research seeks to provide a more effective treatment option for patients suffering from chronic wounds.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic wounds, particularly those with infections related to diabetes or other comorbidities.
Not a fit: Patients with acute wounds or those not affected by chronic infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for chronic wounds, reducing the risk of complications such as infections and amputations.
How similar studies have performed: Other research has shown promise in using ultrasound technology for drug delivery, indicating potential success for this novel approach.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Papadopoulou, Virginie — Univ of North Carolina Chapel Hill
- Study coordinator: Papadopoulou, Virginie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.