Using special materials to control brain activity with sound

Mechanoluminescent nanomaterials for optogenetic neuromodulation

NIH-funded research University of California Riverside · NIH-10846840

This study is exploring new materials that use sound waves to safely activate brain cells, which could help scientists better control neurons with light and improve treatments for conditions that affect thinking and movement.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California Riverside NIH-funded
Lab location1 site (Riverside, United States)
Project IDNIH-10846840 on NIH RePORTER

What this research studies

This research focuses on developing innovative materials that can activate brain cells non-invasively using sound waves. By creating a new type of mechanoluminescent material, the project aims to enhance optogenetic techniques, which allow scientists to control neurons with light. The approach involves synthesizing unique nanomaterials that can effectively modulate neural circuits, potentially leading to better treatments for neurological disorders. Patients may benefit from advancements in understanding and treating conditions affecting cognitive and motor functions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from neurological diseases or disorders that affect cognitive, sensory, or motor functions.

Not a fit: Patients with non-neurological conditions or those who do not have access to the required technology may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new, less invasive treatments for neurological disorders, improving patient outcomes.

How similar studies have performed: Other research has shown promise in using optogenetic techniques for neural modulation, but this specific approach with mechanoluminescent materials is relatively novel.

Where this research is happening

Riverside, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.