Laser particle barcoding to track live cells and their omics in breast cancer
Official title: Laser particles-based spatiotemporal and dynamic single-cell multiomics
Funded at University of California Riverside · NIH-11421522 · Data updated 2026-11-12
A new technique uses special laser-coded particles to follow individual breast cancer cells in real time while linking their live behavior to multi-omics data.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Riverside NIH-funded |
| Lab location | 1 site (Riverside, United States) |
| Project start | September 23, 2025 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $241,739 |
| NIH project number | 5R00HG013129-04 |
| Project ID | NIH-11421522 on NIH RePORTER |
Who could benefit from this research
✓Could help
Breast cancer patients or tissue samples that can provide live cells for barcoding and omics analysis.
✕Less likely to help
This research is basic science and does not involve direct patient treatment; participants are not recruited for a clinical trial.
What this research studies
This project aims to develop a cell barcoding method using laser particles to optical-track single live cells and pair their dynamic life with detailed molecular information. Researchers will capture live cell behavior in real environments or culture, then harvest the same cells for comprehensive omics analysis, including genome, epigenome, transcriptome, and proteome. The approach seeks to connect how cells act and move with their deep molecular profiles, advancing our understanding of breast cancer biology.
Why it matters
Potential benefit: If successful, patients could benefit from more precise insight into how breast cancer cells behave and respond, potentially guiding future personalized therapies.
How similar studies have gone: Preliminary single-cell and spatial omics methods have shown promise, but dynamic live-cell barcoding linked to omics is novel.
Where this research is happening
-
University of California Riverside
Riverside, United States Active
Researchers
- Principal investigator: Wu, Yue Jane — University of California Riverside
- Study coordinator: Wu, Yue Jane
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.