Using radical migration to create new medicines
Official title: Harnessing the Latent Potential of Radical Migration to Drive Synthetic Innovation
Funded at Pennsylvania State University, the · NIH-10940801 · Data updated 2026-11-12
This study is exploring new ways to make medicines more effectively, which could lead to better and more effective treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $383,884 |
| NIH project number | 1R35GM155233-01 |
| Project ID | NIH-10940801 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals who require new pharmaceutical treatments for their medical conditions.
✕Less likely to help
Patients who are not seeking new medication options or those with conditions that do not require pharmaceutical intervention may not benefit from this research.
What this research studies
This research focuses on developing innovative synthetic methods that utilize radical-mediated migrations to enhance the discovery and production of pharmaceuticals. By improving processes like olefin difunctionalizations and stereoselective α-functionalizations of carbonyls, the project aims to overcome existing technical challenges in pharmaceutical synthesis. Patients may benefit from new and more effective medications that can be produced through these advanced synthetic techniques.
Why it matters
Potential benefit: If successful, this research could lead to the development of new and more effective medications for various health conditions.
How similar studies have gone: Other research has shown promise in utilizing radical-mediated approaches for synthetic innovation, indicating potential for success in this novel application.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Nacsa, Eric — Pennsylvania State University, the
- Study coordinator: Nacsa, Eric
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.