Using PET imaging to detect inflammation in atherosclerosis
PET Detection of CCR2 in Human Atherosclerosis
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-10800767
This study is looking at how inflammation affects atherosclerosis, which can lead to heart problems, and it’s testing a new imaging tool to help doctors find the best treatments for patients based on their inflammation levels.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10800767 on ClinicalTrials.gov |
What this research studies
This research investigates the role of inflammation in atherosclerosis, a condition that increases the risk of cardiovascular disease. It aims to develop a new imaging tool that can identify patients with specific inflammatory profiles, helping to determine the most effective treatments for them. The study utilizes a specialized PET radiotracer that targets a specific receptor involved in inflammation, allowing for non-invasive detection of atherosclerotic lesions. By evaluating this imaging technique in human subjects, the research seeks to improve risk stratification and treatment monitoring for patients with atherosclerosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with atherosclerosis, particularly those exhibiting inflammatory symptoms.
Not a fit: Patients without atherosclerosis or those who do not exhibit inflammatory characteristics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients with atherosclerosis.
How similar studies have performed: Previous research has shown promise in using similar imaging techniques to detect inflammation in cardiovascular diseases, indicating potential for success in this approach.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GROPLER, ROBERT J. — WASHINGTON UNIVERSITY
- Study coordinator: GROPLER, ROBERT J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Atherosclerotic Cardiovascular Disease, atherosclerotic disease, atherosclerotic vascular disease