Using personalized brain stimulation to improve hand function after stroke
Developing real-time personalized TMS to target residual corticospinal connections after stroke
This study is exploring a new way to help stroke survivors improve their hand function by using a personalized treatment that gently stimulates the brain at just the right moments, based on their unique brain activity, to boost recovery.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas at Austin NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project ID | NIH-11056094 on NIH RePORTER |
What this research studies
This research investigates how to enhance hand function in stroke survivors by using personalized transcranial magnetic stimulation (TMS) that targets specific brain connections affected by the stroke. The approach involves monitoring brain activity to identify optimal times for TMS application, ensuring that stimulation coincides with strong brain states that promote recovery. By tailoring the treatment to each individual's unique brain patterns, the goal is to maximize the effectiveness of TMS in restoring hand function. This innovative method leverages machine learning to personalize the intervention based on real-time brain activity.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have experienced a stroke and are seeking to improve their hand function.
Not a fit: Patients who have not had a stroke or those with severe cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve hand function in stroke survivors, enhancing their ability to perform daily activities.
How similar studies have performed: Previous research has shown promise in using TMS for stroke rehabilitation, but this personalized approach is relatively novel and untested.
Where this research is happening
Austin, United States
- University of Texas at Austin — Austin, United States (Active)
Researchers
- Principal investigator: Hussain, Sara J — University of Texas at Austin
- Study coordinator: Hussain, Sara J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.