NIH-funded research Sbir 2 grant

Using noninvasive brain stimulation to help treat addiction

Official title: Noninvasive Brain Stimulation for Treating Addiction (Supplement)

Funded at Highland Instruments, INC. · NIH-10999342 · Data updated 2026-11-12

This study is looking at a new, gentle way to help people with opioid use disorder and other addictions by using noninvasive brain stimulation to change brain activity, with the hope of making it easier for them to stay off drugs and feel fewer cravings.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionHighland Instruments, INC.
NIH-funded
Lab location1 site (Cambridge, United States)
Project startSeptember 30, 2019
Project endAugust 31, 2025
Funding year2024
Award (this year)$1,314,672
NIH project number3R44DA049685-03S1
Project IDNIH-10999342 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with opioid use disorder or other addictive disorders who are seeking alternative treatment options.

Less likely to help

Patients who are not struggling with addiction or those who have contraindications for brain stimulation therapies may not benefit from this research.

What this research studies

This research investigates the use of noninvasive brain stimulation (NIBS) as a potential treatment for opioid use disorder and other forms of addiction. The approach aims to alter brain activity to reverse the harmful changes caused by addiction, which could lead to improved treatment outcomes. Patients may receive NIBS sessions that are designed to enhance their ability to abstain from substance use and reduce cravings. The study will evaluate the safety and effectiveness of this innovative treatment method.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for individuals struggling with addiction, potentially reducing overdose deaths and improving recovery rates.

How similar studies have gone: Previous studies have shown promise in using noninvasive brain stimulation for treating various forms of addiction, indicating that this approach may be effective.

Where this research is happening

  • Highland Instruments, INC.
    Cambridge, United States
    Active

Researchers

  • Principal investigator: Wagner, Timothy Andrew — Highland Instruments, INC.
  • Study coordinator: Wagner, Timothy Andrew

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.