Using natural compounds to improve healing for chronic wounds
Glycosaminoglycan-enabled technologies to reprogram chronic inflammatory states
This work explores how special natural compounds called glycosaminoglycans can help balance inflammation and promote better healing for people with chronic wounds.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11168858 on NIH RePORTER |
What this research studies
When you get an injury, your body's natural response is inflammation to protect against germs and remove damaged tissue, but sometimes this process gets stuck and leads to chronic wounds that don't heal. Our team is looking at how a specific natural compound, chondroitin sulfate (CS), can help reset this inflammatory response. We aim to find the right way to deliver CS so it encourages healing without creating new problems. This involves understanding how CS affects immune cells and the surrounding tissue at the injury site.
Who could benefit from this research
Good fit: This foundational work is for patients experiencing chronic wounds or other conditions related to persistent inflammation, as it aims to develop new therapeutic strategies.
Not a fit: Patients without chronic inflammatory conditions or wounds would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new treatments that help chronic wounds heal more effectively by rebalancing the body's inflammatory response.
How similar studies have performed: While chondroitin sulfate is known to affect inflammation, this project is novel in its focus on controlled delivery to balance inflammation and promote tissue repair.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Dumont, Courtney Margaret — University of Miami School of Medicine
- Study coordinator: Dumont, Courtney Margaret
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.