Using glycosaminoglycans to improve healing in chronic inflammation
Official title: Glycosaminoglycan-enabled technologies to reprogram chronic inflammatory states
Funded at University of Miami School of Medicine · NIH-10939846 · Data updated 2026-11-12
This study is looking at how a substance called chondroitin sulfate can help reduce long-lasting inflammation and speed up healing for people with injuries, aiming to improve recovery and prevent ongoing wounds.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $351,750 |
| NIH project number | 1R35GM155140-01 |
| Project ID | NIH-10939846 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with chronic wounds or those experiencing prolonged inflammatory responses due to traumatic injuries.
✕Less likely to help
Patients with acute injuries that heal without complications may not receive significant benefits from this research.
What this research studies
This research investigates how glycosaminoglycans, specifically chondroitin sulfate, can be used to manage chronic inflammation and enhance tissue repair. It focuses on understanding the role of these substances in regulating immune responses and cytokine signaling at injury sites. By balancing inflammation and tissue regeneration, the research aims to prevent chronic wounds and improve recovery outcomes for patients with traumatic injuries. The approach includes both local delivery and modulation of immune cell behavior to promote healing.
Why it matters
Potential benefit: If successful, this research could lead to improved healing processes for patients suffering from chronic wounds and inflammatory conditions.
How similar studies have gone: Previous research has shown promise in using glycosaminoglycans for modulating inflammation, suggesting potential success for this approach.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Dumont, Courtney Margaret — University of Miami School of Medicine
- Study coordinator: Dumont, Courtney Margaret
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.