Using fluorescent imaging to study brain and body functions in zebrafish
Fluorescent polysomnography and MCH neurogenetics
['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-10614463
This study is exploring a new way to watch how the brain and body work together during sleep using zebrafish, which could help us learn more about sleep problems and mental health issues, and hopefully lead to better treatments for people who struggle with these conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10614463 on ClinicalTrials.gov |
What this research studies
This research investigates a new method called fluorescence-based polysomnography (fPSG) to observe brain and body functions in zebrafish. By using advanced imaging techniques, researchers aim to capture real-time activity in the brain, muscles, and heart, which could help in understanding sleep patterns and disorders. The study focuses on how these functions relate to mental health and neurological conditions, potentially providing insights into the underlying mechanisms of these disorders. Patients may benefit from the findings as they could lead to new diagnostic tools or treatments for sleep and psychiatric disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with sleep disorders or psychiatric conditions.
Not a fit: Patients with conditions unrelated to sleep or mental health may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and treatments for sleep and mental health disorders.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for studying brain functions, but this specific approach in zebrafish is relatively novel.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MOURRAIN, PHILIPPE — STANFORD UNIVERSITY
- Study coordinator: MOURRAIN, PHILIPPE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Mental disorders, Mental health disorders, Psychiatric Disease, Psychiatric Disorder, psychological disorder