NIH-funded research R01 grant

Using exercise to help adults with high anxiety sensitivity quit smoking

Official title: Efficacy and implementation of exercise-based smoking cessation treatment for adults with high anxiety sensitivity

Funded at University of Texas at Austin · NIH-10880577 · Data updated 2026-11-12

This study is looking at how doing high-intensity exercise can help adults who feel very anxious and want to quit smoking, by improving their mood and reducing anxiety, so they can have a better chance of successfully stopping smoking.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin
NIH-funded
Lab location1 site (Austin, United States)
Project startJuly 3, 2023
Project endJune 30, 2028
Funding year2024
Award (this year)$516,606
NIH project number5R01CA273221-02
Project IDNIH-10880577 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults over 21 years old who experience high anxiety sensitivity and are seeking help to quit smoking.

Less likely to help

Patients who do not have high anxiety sensitivity or who are not interested in using exercise as a method for smoking cessation may not benefit from this research.

What this research studies

This research investigates how high-intensity exercise can aid adults with high anxiety sensitivity in quitting smoking. It focuses on the relationship between anxiety, mood disorders, and smoking behavior, aiming to develop a treatment that addresses both smoking cessation and mental health. Participants will engage in exercise programs designed to reduce anxiety sensitivity and improve mood, potentially leading to better smoking cessation outcomes. The study will follow participants over time to assess the effectiveness of this approach.

Why it matters

Potential benefit: If successful, this research could provide a new, effective method for helping individuals with high anxiety sensitivity quit smoking and improve their mental health.

How similar studies have gone: Previous research has shown that exercise can be beneficial for mental health and smoking cessation, suggesting that this approach may be effective.

Where this research is happening

  • University of Texas at Austin
    Austin, United States
    Active

Researchers

  • Principal investigator: Smits, Jasper — University of Texas at Austin
  • Study coordinator: Smits, Jasper

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.