Using electrical stimulation to improve recovery after stroke

Transcranial Electrical Stimulation in Stroke EaRly After onset Clinical Trial-2 (TESSERACT 2)

NIH-funded research University of California Los Angeles · NIH-10984220

This study is looking at a gentle electrical treatment called C-tDCS to see if it can help people who have had a recent stroke by protecting their brain and improving their recovery, especially for those who can’t use standard treatments.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10984220 on NIH RePORTER

What this research studies

This research investigates the use of cathodal transcranial direct current stimulation (C-tDCS) as a non-invasive treatment for patients who have suffered an acute ischemic stroke (AIS). The approach involves applying a weak electrical current through electrodes placed on the scalp to target ischemic brain tissue, potentially protecting it from further damage and enhancing blood flow. The study aims to evaluate the effectiveness of this technique in improving patient outcomes, particularly in those who are not candidates for traditional reperfusion therapies. By focusing on individual patient needs, the research seeks to provide a tailored treatment option that could lead to better recovery rates.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have recently experienced an acute ischemic stroke and are not eligible for standard reperfusion therapies.

Not a fit: Patients who have had a hemorrhagic stroke or those who are too far along in their recovery may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for stroke patients, potentially improving their recovery and quality of life.

How similar studies have performed: Previous studies have shown promising results with similar neuromodulatory techniques, indicating potential for success in this novel application.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.