Using Driving Pressure to Improve Lung Ventilation in Patients with ARDS
Driving Pressure as a Target for Lung-Protective Ventilation
This study is looking at a new way to help people with acute respiratory distress syndrome (ARDS) breathe better using a special method of mechanical ventilation that focuses on reducing pressure in the lungs, to see if it can improve their recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10918270 on NIH RePORTER |
What this research studies
This research focuses on improving the management of acute respiratory distress syndrome (ARDS) by evaluating a new approach to mechanical ventilation that targets low Driving Pressure. Patients with ARDS often require mechanical ventilation, which can sometimes cause additional lung injury. The study aims to determine if a Driving Pressure-guided ventilation strategy can lead to better outcomes for patients suffering from this serious condition. By conducting this research, the team hopes to provide insights that could enhance the safety and effectiveness of ventilation practices in critical care settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with acute respiratory distress syndrome requiring mechanical ventilation.
Not a fit: Patients with chronic respiratory conditions or those who do not require mechanical ventilation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce mortality rates and improve recovery for patients with ARDS.
How similar studies have performed: Previous observational studies have suggested that targeting Driving Pressure in mechanical ventilation may improve patient outcomes, indicating a promising avenue for further investigation.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Sahetya, Sarina — Johns Hopkins University
- Study coordinator: Sahetya, Sarina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.