Using deep learning to understand genetics at the single-cell level
Official title: Deep Learning for Single-Cell Genetics
Funded at University of Florida · NIH-11021325 · Data updated 2026-11-12
This study is looking at how our genes and cells work together to help us understand complex diseases better, so that patients can get clearer insights into their conditions and potentially improve their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | May 1, 2025 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $359,490 |
| NIH project number | 1R35GM157219-01 |
| Project ID | NIH-11021325 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with complex diseases that have a genetic component.
✕Less likely to help
Patients with purely environmental or non-genetic conditions may not receive any benefit from this research.
What this research studies
This research focuses on integrating advanced single-cell genomic data with genetic analysis to better understand complex diseases. By employing deep learning techniques, the project aims to link genetic variants to specific cellular processes, which can help identify disease-causing factors. The research utilizes large datasets from biobanks and aims to develop new methodologies that can enhance gene discovery and disease prediction. Patients may benefit from improved understanding of their conditions through more precise genetic insights.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and targeted therapies for complex diseases based on genetic insights.
How similar studies have gone: Other research has shown promise in using deep learning for genetic analysis, indicating that this approach could yield significant advancements.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Zhang, Sai — University of Florida
- Study coordinator: Zhang, Sai
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.