Using cannabidiol to improve cognitive behavioral therapy for anxiety

Cannabidiol-enhanced cognitive behavioral therapy for generalized anxiety disorder

NIH-funded research Wayne State University · NIH-11124492

This study is looking at whether adding cannabidiol, a safe part of cannabis, can make cognitive behavioral therapy (CBT) more effective for people with generalized anxiety disorder, helping them better manage their emotions and anxiety.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWayne State University NIH-funded
Lab location1 site (Detroit, United States)
Project IDNIH-11124492 on NIH RePORTER

What this research studies

This research investigates the potential of cannabidiol, a non-intoxicating component of cannabis, to enhance the effectiveness of cognitive behavioral therapy (CBT) for individuals with generalized anxiety disorder (GAD). The study aims to address the challenges faced by patients who struggle with emotion regulation, which is crucial for managing anxiety symptoms. By combining cannabidiol with CBT, the researchers hope to improve brain activity related to emotion processing and regulation, ultimately leading to better treatment outcomes. Participants will receive both therapies to evaluate their combined effects on anxiety management.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing symptoms of generalized anxiety disorder.

Not a fit: Patients who do not have generalized anxiety disorder or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment options for individuals suffering from generalized anxiety disorder.

How similar studies have performed: Previous research has shown promising results in using cannabinoids to enhance emotional regulation in anxiety-related conditions, suggesting potential success for this combined approach.

Where this research is happening

Detroit, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Anxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.