Using broccoli sprouts to reduce gut inflammation
Official title: Harnessing gut microbiota to reduce inflammation using broccoli-sprout diets
Funded at University of Maine Orono · NIH-10514847 · Data updated 2026-11-12
This study is looking at how eating certain types of broccoli sprouts might help improve gut health and reduce inflammation for people with inflammatory bowel disease (IBD), so you can learn how your diet could make a difference in managing your condition.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maine Orono NIH-funded |
| Lab location | 1 site (Orono, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $436,046 |
| NIH project number | 1R15DK133826-01 |
| Project ID | NIH-10514847 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with inflammatory bowel disease, such as Crohn's disease or ulcerative colitis.
✕Less likely to help
Patients without inflammatory bowel disease or those who do not respond to dietary changes may not benefit from this research.
What this research studies
This research investigates how specific preparations of broccoli sprouts can change gut microbiota to reduce inflammation associated with inflammatory bowel disease (IBD). By examining the effects of these dietary changes on gut health, the study aims to identify mechanisms that could lead to new dietary therapies for IBD. The research involves both animal models and plans for future human applications, focusing on the transformation of inactive compounds into beneficial bioactives through gut bacteria. Patients may benefit from a better understanding of how diet can influence their condition.
Why it matters
Potential benefit: If successful, this research could lead to new dietary interventions that help manage or reduce symptoms of inflammatory bowel disease.
How similar studies have gone: Previous research has shown promising results in using dietary interventions to influence gut health, suggesting potential success for this approach.
Where this research is happening
-
University of Maine Orono
Orono, United States Active
Researchers
- Principal investigator: Pellegrini, Suzanne Ishaq — University of Maine Orono
- Study coordinator: Pellegrini, Suzanne Ishaq
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.